Protein Alignment Akr1B and akr1a1b

DIOPT Version :9

• Sequence 1: NP_001261716.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: XP_005166342.1
• Gene: akr1a1b / 799805
• ZFINID: ZDB-GENE-050417-118
• Length: 351
• Species: Danio rerio
• Alignment Length: 344
• Identity: 163/344 - (47%)
• Similarity: 221/344 - (64%)
• Gaps: 23/344 - (6%)

  Fly    27 FMWCQKEYAR--APKV------VCLDGNEIPVIGLGTFNSPKGQVTEAVKVAIDAGYRHIDCAYV 83
            |:...|.|.|  |.|:      |...|.::|::||||:.|..|.|.:||..|:::||||||||.:
Zfish    11 FIHSHKFYCRRMAHKMSMNDFAVLSTGRKMPLLGLGTWKSEPGLVKQAVIWALESGYRHIDCAPI 75

  Fly    84 YQNEDEVGDGVEAKI-KEGVVKREDLFITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHW 147
            |.||.|:|:..:..: .:..::|||:|:|||||||.|.||.|:.:|..||..|||:|||||||||
Zfish    76 YANEPEIGEAFQETMGPDKGIRREDVFVTSKLWNTKHHPDDVEPSLLKTLKDLKLEYLDLYLIHW 140

  Fly   148 PMGYKEGCDLFPTDKDGKTLYSPVDYVDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATIP 212
            |..::.|...||..:||..||..:||..||.||||||.:|||::||:||||.|||:.:|.||:|.
Zfish   141 PYAFQRGDTPFPRKEDGTLLYDDIDYKLTWAAMEKLVGKGLVRAIGLSNFNSRQIDDILSVASIK 205

  Fly   213 PVTNQIECHPYLTQKKLIDFCKSKDITITAYSPLGSPNRPWAKAGDPVILEEAKIKEIAAKKKKT 277
            |...|:|.||||.|.:|:..|:.:.:.:|||||||||:|.|....:||:|||..|..:|.|..||
Zfish   206 PTVLQVESHPYLAQVELLSHCRDRGLVMTAYSPLGSPDRAWKHPDEPVLLEEPAIAALAKKYNKT 270

  Fly   278 PGQILIRYQVQRANIVIPKSVTKDRIESNFQVFDFELTPEEIE-----------IIESFECNGRL 331
            |.||:||:|.||..:.||||:|:.||:.|.|||||.|..||:.           |:.:...:|:.
Zfish   271 PAQIIIRWQTQRGVVTIPKSITQSRIKENIQVFDFTLESEEMSQVTALHRGWRYIVPTITVDGKS 335

  Fly   332 VPLLNQYGHPHHPFEKDEY 350
            ||  ...||||:|| .|.|
Zfish   336 VP--RDAGHPHYPF-NDSY 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_001261716.1	ARA1	38..316	CDD:223729	144/284 (51%)
		Tas	45..>248	CDD:223739	105/203 (52%)
akr1a1b	XP_005166342.1	ARA1	27..324	CDD:223729	145/296 (49%)
		Tas	36..320	CDD:223739	144/283 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1770
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.760