Protein Alignment Akr1B and Akr1c21

DIOPT Version :9

• Sequence 1: NP_001261716.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_084177.2
• Gene: Akr1c21 / 77337
• MGIID: 1924587
• Length: 323
• Species: Mus musculus
• Alignment Length: 317
• Identity: 149/317 - (47%)
• Similarity: 206/317 - (64%)
• Gaps: 7/317 - (2%)

  Fly    40 VVCLDGNEIPVIGLGT---FNSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEG 101
            |:..|||.|||:|.||   ...||.:..|..|:|||||:.|.|.|.||..||.||:.:.:||.:|
Mouse     8 VILNDGNFIPVLGFGTALPLECPKSKAKELTKIAIDAGFHHFDSASVYNTEDHVGEAIRSKIADG 72

  Fly   102 VVKREDLFITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDGKT 166
            .|:|||:|.|||:|.|...|:||:::||.:|..|:..|:||||||:||..|.|.:.||.|:.||.
Mouse    73 TVRREDIFYTSKVWCTSLHPELVRASLERSLQKLQFDYVDLYLIHYPMALKPGEENFPVDEHGKL 137

  Fly   167 LYSPVDYVDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATI--PPVTNQIECHPYLTQKKL 229
            ::..||...||:||||..:.||.|||||||||.||:|.:|....:  .||.||:||||||.|.||
Mouse   138 IFDRVDLCATWEAMEKCKDAGLTKSIGVSNFNYRQLEMILNKPGLKYKPVCNQVECHPYLNQMKL 202

  Fly   230 IDFCKSKDITITAYSPLGSPN-RPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIV 293
            :||||||||.:.||..||:.. ..|.....||:|:|..:..:|.|..:||..|.:|||:||..:|
Mouse   203 LDFCKSKDIVLVAYGVLGTQRYGGWVDQNSPVLLDEPVLGSMAKKYNRTPALIALRYQLQRGIVV 267

  Fly   294 IPKSVTKDRIESNFQVFDFELTPEEIEIIESFECNGRLVPLLNQYGHPHHPFEKDEY 350
            :..|:.::||:.|.|||:|:|:.|::::::....|.|.:|.....|||:.|| .|||
Mouse   268 LNTSLKEERIKENMQVFEFQLSSEDMKVLDGLNRNMRYIPAAIFKGHPNWPF-LDEY 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_001261716.1	ARA1	38..316	CDD:223729	137/281 (49%)
		Tas	45..>248	CDD:223739	109/207 (53%)
Akr1c21	NP_084177.2	AKR_AKR1C1-35	6..308	CDD:381334	140/299 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11732
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.930