Protein Alignment Akr1B and Akr1c12

DIOPT Version :9

• Sequence 1: NP_001261716.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_038805.2
• Gene: Akr1c12 / 622402
• MGIID: 1351661
• Length: 323
• Species: Mus musculus
• Alignment Length: 313
• Identity: 145/313 - (46%)
• Similarity: 207/313 - (66%)
• Gaps: 7/313 - (2%)

  Fly    44 DGNEIPVIGLGTFNS---PKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEGVVKR 105
            ||:.||.:|.||:..   ||.:..||..:|:|.||||:|.||.||.|:|:|..:::|||.|||||
Mouse    12 DGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQAIQSKIKAGVVKR 76

  Fly   106 EDLFITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDGKTLYSP 170
            ||||||:|||....||:|||.|||.:|.||:|.|:||||||:|:..|.|.:..|.|::||.|...
Mouse    77 EDLFITTKLWCGCFRPELVKPALEKSLKSLQLDYVDLYLIHYPVPMKPGDNESPLDENGKFLLDT 141

  Fly   171 VDYVDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATI--PPVTNQIECHPYLTQKKLIDFC 233
            ||:.|||:.:|:..:.||||||||||||.||:||:|....:  .||.||:|||.||.|.||:|:|
Mouse   142 VDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPGLKYKPVCNQVECHLYLNQSKLLDYC 206

  Fly   234 KSKDITITAYSPLGSPN-RPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIPKS 297
            |||||.:.||..||:.. :.|.....||:|.:..:.::|.:.|::|..|.:||..||..:.:.:|
Mouse   207 KSKDIVLVAYGALGTQRYKEWVDQNSPVLLNDPVLCDVAKRNKRSPALIALRYLFQRGIVPLAQS 271

  Fly   298 VTKDRIESNFQVFDFELTPEEIEIIESFECNGRLVPLLNQYGHPHHPFEKDEY 350
            ..::.:..|.|||:|:|:||:::.::....|.|.:|......||.:|| .:||
Mouse   272 FKENEMRENLQVFEFQLSPEDMKTLDGLNKNFRYLPAEFLADHPEYPF-SEEY 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_001261716.1	ARA1	38..316	CDD:223729	134/277 (48%)
		Tas	45..>248	CDD:223739	113/207 (55%)
Akr1c12	NP_038805.2	Tas	6..297	CDD:223739	136/284 (48%)
		ARA1	7..307	CDD:223729	138/294 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11732
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.930