DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Akr1B and akr1d1

DIOPT Version :9

Sequence 1:	NP_001261716.1	Gene:	Akr1B / 39304	FlyBaseID:	FBgn0086254	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_001025609.1	Gene:	akr1d1 / 594997	XenbaseID:	XB-GENE-947167	Length:	326	Species:	Xenopus tropicalis

Alignment Length:	325	Identity:	164/325 - (50%)
Similarity:	209/325 - (64%)	Gaps:	11/325 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 EYARAPKVVCLDGNEIPVIGLGTFNS----PKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDG 93
            |:.|.|   ..|||.|||:||||::|    |||...||||:|||.||||||.||||.||.|||..
Frog     6 EHHRIP---LNDGNSIPVLGLGTYSSPRTTPKGTCLEAVKLAIDLGYRHIDGAYVYYNEHEVGQA 67

  Fly    94 VEAKIKEGVVKREDLFITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLF 158
            :..||.||.|||||:|...|||||.|.|:||:..||.||.:|:|.|:|||:|..||.:|.|.:::
Frog    68 IREKIAEGKVKREDIFYCGKLWNTCHPPELVRPTLEKTLKTLQLDYVDLYIIELPMAFKPGDEIY 132

  Fly   159 PTDKDGKTLYSPVDYVDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATI--PPVTNQIECH 221
            |.|.:||.||...|...||:|:|:..:.|||||||||||||||:|.:|....:  .|.|||:|||
Frog   133 PRDANGKYLYHKTDLCATWEALEECKDAGLVKSIGVSNFNRRQLELILNKPGLKYKPATNQVECH 197

  Fly   222 PYLTQKKLIDFCKSKDITITAYSPLGS-PNRPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRY 285
            ||.||.||::|....||....|||:|: .:..|.....|.:|::..:..|..|..||..|:.:|:
Frog   198 PYFTQPKLLEFSGQHDIVTVGYSPIGTCRDETWVNVSSPPLLKDPLLNAIGKKYNKTAAQVALRF 262

  Fly   286 QVQRANIVIPKSVTKDRIESNFQVFDFELTPEEIEIIESFECNGRLVPLLNQYGHPHHPFEKDEY 350
            ..||...|||||...|||:.|||:|||.||.:|::.||:...|.|.|.||....||.:|| ||||
Frog   263 NAQRGVAVIPKSFNPDRIKENFQIFDFSLTDKEMKDIEALNKNVRYVELLMWSDHPEYPF-KDEY 326

Fly 351 350
Frog 327 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_001261716.1	ARA1	38..316	CDD:223729	145/284 (51%)
Akr1B	NP_001261716.1	Tas	45..>248	CDD:223739	116/208 (56%)
akr1d1	NP_001025609.1	ARA1	9..309	CDD:223729	152/302 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11732
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.110