Protein Alignment Akr1B and akr1b1.2

DIOPT Version :10

• Sequence 1: NP_729726.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_001070715.1
• Gene: akr1b1.2 / 553452
• ZFINID: ZDB-GENE-041210-132
• Length: 316
• Species: Danio rerio
• Alignment Length: 311
• Identity: 183/311 - (58%)
• Similarity: 230/311 - (73%)
• Gaps: 9/311 - (2%)

  Fly    45 GNEIPVIGLGTFNSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEGVVKREDLF 109
            |.::|::||||:.||.|:|.||||.||.|||||||.|.||.||.|||:|::|.||:||||||:||
Zfish    10 GADMPILGLGTWKSPPGKVAEAVKAAIAAGYRHIDGAAVYNNETEVGEGIKAMIKDGVVKREELF 74

  Fly   110 ITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDGKTLYSPVDYV 174
            :.||||.|||...|||.|.:.|||.|.|.||||||||||||:|.|.:.||.|.:|.|:.....::
Zfish    75 VVSKLWCTFHEKALVKGACQKTLSDLNLDYLDLYLIHWPMGFKSGSEQFPLDSEGLTIGDDSSFL 139

  Fly   175 DTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATI--PPVTNQIECHPYLTQKKLIDFCKSKD 237
            |||:.||:||:.||||:||:|||||.|||.:|....:  .|..||:||||||||.|||.:|:||.
Zfish   140 DTWEGMEELVDAGLVKAIGISNFNREQIEAILNKPGLKYKPANNQVECHPYLTQDKLISYCQSKG 204

  Fly   238 ITITAYSPLGSPNRPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIPKSVTKDR 302
            ||:|||||||||:|||||..||.:|::..||.||.|.|||..|:|||:|:||..||||||:|..|
Zfish   205 ITVTAYSPLGSPDRPWAKPEDPSLLDDPNIKAIAEKHKKTTAQVLIRFQIQRNVIVIPKSITPQR 269

  Fly   303 IESNFQVFDFELTPEEIEIIESFECNGRLVPL---LKDAGTHKYYPFHDEY 350
            |:.|||||||||:.|:::.|.||..|.|..|:   :|    |:.|||:.||
Zfish   270 IQENFQVFDFELSEEDMKTILSFNRNFRACPMHWGVK----HRDYPFNAEY 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_729726.1	AKR_SF	45..350	CDD:444925	181/309 (59%)
akr1b1.2	NP_001070715.1	AKR_SF	10..316	CDD:444925	181/309 (59%)