Protein Alignment Akr1B and akr1a1

DIOPT Version :10

• Sequence 1: NP_729726.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_001016137.1
• Gene: akr1a1 / 548891
• XenbaseID: XB-GENE-1014353
• Length: 327
• Species: Xenopus tropicalis
• Alignment Length: 320
• Identity: 169/320 - (52%)
• Similarity: 218/320 - (68%)
• Gaps: 19/320 - (5%)

  Fly    45 GNEIPVIGLGTFNSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEGV-----VK 104
            |.:||:|||||:.|..|||.:|||.|:..||||||||:||.||.|||:.    |||.|     :.
 Frog    13 GQKIPLIGLGTWKSAPGQVKDAVKYALGVGYRHIDCAFVYGNETEVGEA----IKESVGSDKGLS 73

  Fly   105 REDLFITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDGKTLYS 169
            ||::|:||||||..|.||.|:.||..||..|:|.||||||:|||..:|.|..:||.:.||...|.
 Frog    74 REEVFVTSKLWNNKHHPDDVECALRKTLQDLQLDYLDLYLMHWPYAFKRGDQIFPQNPDGSVQYD 138

  Fly   170 PVDYVDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATIPPVTNQIECHPYLTQKKLIDFCK 234
            ..||.||||||||||::||.|:||:||||:|||:.::.:||:.|...|:||||||.|.:||.:|.
 Frog   139 LTDYKDTWKAMEKLVKQGLTKAIGLSNFNKRQIDDIISIATVKPAVLQVECHPYLAQNELIAYCH 203

  Fly   235 SKDITITAYSPLGSPNRPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIPKSVT 299
            :..:..|.|||||||:|.|.|..|||:|||..|..:|.|..|:..|||:|:||||..:.||||||
 Frog   204 AHGLVFTGYSPLGSPDRSWRKPEDPVLLEEPGIIAMAKKYGKSEAQILLRWQVQRKVVSIPKSVT 268

  Fly   300 KDRIESNFQVFDFELTPEEIEIIESFECNGR-LVPLL--------KDAGTHKYYPFHDEY 350
            ..||..|||||||.|:.||:::|.:...|.| ::||:        :||| |..|||:|.|
 Frog   269 PTRILQNFQVFDFSLSEEEMQLIGALNKNWRYIIPLITVNGKSVPRDAG-HPLYPFNDPY 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_729726.1	AKR_SF	45..350	CDD:444925	168/318 (53%)
akr1a1	NP_001016137.1	AKR_AKR1A1-4	10..314	CDD:381332	160/304 (53%)