Protein Alignment Akr1B and akr1b1

DIOPT Version :10

• Sequence 1: NP_729726.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_001011130.1
• Gene: akr1b1 / 496546
• XenbaseID: XB-GENE-5821742
• Length: 318
• Species: Xenopus tropicalis
• Alignment Length: 308
• Identity: 188/308 - (61%)
• Similarity: 232/308 - (75%)
• Gaps: 3/308 - (0%)

  Fly    45 GNEIPVIGLGTFNSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEGVVKREDLF 109
            |.::|::||||:.|..|:||.||..||:.||||:|||||||||:|||:|::.|||||:|||||||
 Frog    12 GAQMPIVGLGTWKSEPGKVTAAVAKAIEVGYRHLDCAYVYQNENEVGEGIQQKIKEGLVKREDLF 76

  Fly   110 ITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDGKTLYSPVDYV 174
            :.||||:|||...:||.|.:.|||.|||.||||||:|||.|::.|..|||.|.:|..::|...::
 Frog    77 VVSKLWSTFHDKSMVKGACQKTLSDLKLDYLDLYLVHWPTGFQAGDALFPLDNEGCVIHSNTHFL 141

  Fly   175 DTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATI--PPVTNQIECHPYLTQKKLIDFCKSKD 237
            |||:.||:||:.||||:||:|||||.|||::|....:  .|..:|.|||||||||||||.|:||.
 Frog   142 DTWEGMEELVDAGLVKAIGISNFNREQIEQLLNKPGLKHKPAVHQFECHPYLTQKKLIDLCQSKG 206

  Fly   238 ITITAYSPLGSPNRPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIPKSVTKDR 302
            |.:|||||||||:|||||..||.:|||.||||||.|..||..|:|||:.:||..:|||||||..|
 Frog   207 IVVTAYSPLGSPDRPWAKPEDPSLLEEPKIKEIAKKYNKTSAQVLIRFHIQRNVVVIPKSVTPAR 271

  Fly   303 IESNFQVFDFELTPEEIEIIESFECNGRLVPLLKDAGTHKYYPFHDEY 350
            ||.|||||||||:||:.|.|.||| .|..|..|..|..||.||||..|
 Frog   272 IEENFQVFDFELSPEDTEAIFSFE-RGWRVCALSSAKKHKDYPFHAAY 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_729726.1	AKR_SF	45..350	CDD:444925	187/306 (61%)
akr1b1	NP_001011130.1	AKR_AKR1B1-19	12..318	CDD:381333	187/306 (61%)