Protein Alignment Akr1B and akr1c4

DIOPT Version :10

• Sequence 1: NP_729726.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: XP_031753743.1
• Gene: akr1c4 / 496490
• XenbaseID: XB-GENE-5895888
• Length: 328
• Species: Xenopus tropicalis
• Alignment Length: 341
• Identity: 145/341 - (42%)
• Similarity: 212/341 - (62%)
• Gaps: 31/341 - (9%)

  Fly    23 KPERFMWCQKEYARAPKVVCLDGNEIPVIGLGTFNS---PKGQVTEAVKVAIDAGYRHIDCAYVY 84
            :|..|:      .:..::...|||.|||:||||:.|   ||...|||.|:|||.|||||||||:|
 Frog     6 QPSMFL------TKDTRLTLHDGNAIPVMGLGTYASAEVPKSDGTEATKLAIDLGYRHIDCAYIY 64

  Fly    85 QNEDEVGDGVEAKIKEGVVKREDLFITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPM 149
            .||.::|:.:.:||.:|.||||::|.|.|||.:|..|:||:..||.:|.:|:|.||||:::|||.
 Frog    65 GNEVQIGEAIRSKIADGTVKREEIFYTGKLWCSFFSPNLVRQGLEASLKALQLDYLDLFIMHWPF 129

  Fly   150 GYKEGCDLFPTDKDGKTLYSPVDYVD-----TWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVA 209
            ..|      |:|....   .|:|:.|     ||:|:|...:.|||||||||||||||:||:|...
 Frog   130 SVK------PSDAHSN---QPLDFDDVDFCLTWEALEGCKDAGLVKSIGVSNFNRRQLERLLSKP 185

  Fly   210 TI--PPVTNQIECHPYLTQKKLIDFCKSKDITITAYSPLGSP-NRPWAKAGDPVILEEAKIKEIA 271
            .:  .||.||:|.|.||.|.||.::||..:|.:.|||.||:. :..|.....||:||:..::.:|
 Frog   186 GLKYKPVCNQVEYHVYLNQSKLHEYCKCHNIVLVAYSVLGTARDNTWVDPNSPVLLEDPVLRSVA 250

  Fly   272 AKKKKTPGQILIRYQVQRANIVIPKSVTKDRIESNFQVFDFELTPEEIEIIESFECNGRLV--PL 334
            ||..::|.::.:|:.:|:..:|:.||....|::.|..||:|||.||::|:::....|.|..  .:
 Frog   251 AKYNRSPAEVAMRFILQKGAVVLAKSFNPTRLKQNLGVFEFELKPEDMEMLDGLNRNLRYAQFTV 315

  Fly   335 LKDAGTHKYYPFHDEY 350
            :|.   |..|||||||
 Frog   316 MKQ---HPEYPFHDEY 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_729726.1	AKR_SF	45..350	CDD:444925	140/317 (44%)
akr1c4	XP_031753743.1	AKR_SF	15..313	CDD:444925	134/306 (44%)