Protein Alignment Akr1B and akr1a1a

DIOPT Version :9

• Sequence 1: NP_001261716.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_001003783.1
• Gene: akr1a1a / 445326
• ZFINID: ZDB-GENE-040808-44
• Length: 324
• Species: Danio rerio
• Alignment Length: 311
• Identity: 155/311 - (49%)
• Similarity: 212/311 - (68%)
• Gaps: 10/311 - (3%)

  Fly    45 GNEIPVIGLGTFNSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEG-VVKREDL 108
            |..:|.:||||:.|..|||.:||..|:|.||||||||..|.||.|||:.:..::..| .::|:|:
Zfish    10 GQRMPTVGLGTWKSAPGQVKQAVLAALDCGYRHIDCAAAYSNEREVGEALTERLGPGKSLRRDDI 74

  Fly   109 FITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDGKTLYSPVDY 173
            |:|||||||.|.||.|:.|...:||.|:|.|||||||||||.:..|.:|.|...||...|....|
Zfish    75 FVTSKLWNTKHHPDDVEEACRRSLSDLRLSYLDLYLIHWPMAFGRGDELIPRHPDGTIQYDDTHY 139

  Fly   174 VDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATIPPVTNQIECHPYLTQKKLIDFCKSKDI 238
            .|||.||||||::||.|:||:||||.:||:.:|.:|...||.||:||||||.|.:|...|.|:::
Zfish   140 RDTWAAMEKLVDQGLAKAIGLSNFNAKQIDDILSIAKHKPVVNQVECHPYLVQAELASHCWSRNL 204

  Fly   239 TITAYSPLGSPNRPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIPKSVTKDRI 303
            |:|||||||||:|||...|:.::|::.::..||....|||.|::||:.:||..:.||||||..||
Zfish   205 TVTAYSPLGSPDRPWVTPGEALLLDDPRVVGIAKSYNKTPAQVIIRWHIQRGVVCIPKSVTPSRI 269

  Fly   304 ESNFQVFDFELTPEEIEIIESFECNGR-LVPLLNQYG--------HPHHPF 345
            :.|.:||||:|:.|::.:||||..|.| ::|.:.:.|        |||.||
Zfish   270 KQNIEVFDFKLSDEDMRLIESFNRNERFIIPTVIKDGQKVWRDANHPHFPF 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_001261716.1	ARA1	38..316	CDD:223729	141/271 (52%)
		Tas	45..>248	CDD:223739	109/203 (54%)
akr1a1a	NP_001003783.1	ARA1	1..297	CDD:223729	147/286 (51%)
		Tas	14..300	CDD:223739	147/285 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	1	1.000	-	-		otm25723
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1770
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.760