Protein Alignment Akr1B and Akr1c19

DIOPT Version :9

• Sequence 1: NP_001261716.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_001013807.2
• Gene: Akr1c19 / 432720
• MGIID: 2653678
• Length: 323
• Species: Mus musculus
• Alignment Length: 318
• Identity: 158/318 - (49%)
• Similarity: 217/318 - (68%)
• Gaps: 17/318 - (5%)

  Fly    44 DGNEIPVIGLGTF-------NSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEG 101
            |||.||.:|.||:       |.|    .||:.:|::||:||||.|||||.|:.||..:.:||..|
Mouse    12 DGNFIPALGFGTYKPEEVNENKP----LEAIHLALEAGFRHIDTAYVYQTENHVGQAIRSKIAAG 72

  Fly   102 VVKREDLFITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDGKT 166
            :|||||:|:|:|||.|||||:||:|.||.:|.:|:|.|.||||||:|:..|.|.||||.|:.|||
Mouse    73 LVKREDIFLTTKLWCTFHRPELVRSNLEKSLKNLQLDYADLYLIHYPVQMKPGEDLFPEDEHGKT 137

  Fly   167 LYSPVDYVDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATI--PPVTNQIECHPYLTQKKL 229
            |:..||...||:||||..:.||||||||||||.||:|::|....:  .||.||:|||.||.|:||
Mouse   138 LFDTVDICATWEAMEKCKDAGLVKSIGVSNFNSRQLEKILNKPGLKYKPVCNQVECHLYLNQRKL 202

  Fly   230 IDFCKSKDITITAYSPLGSPNRP--WAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANI 292
            :::||||||.:.||..||| .||  |.....||:|.:..:.::|.|.|::|.||.:||.:||..:
Mouse   203 LNYCKSKDIVLVAYCALGS-QRPKRWVDPSSPVLLNDPILCDMAKKHKRSPAQIALRYHLQRGIV 266

  Fly   293 VIPKSVTKDRIESNFQVFDFELTPEEIEIIESFECNGRLVPLLNQYGHPHHPFEKDEY 350
            |:.:|..::.|:.|.|||:|||..|:::|::|.:.|.|..|.....|||.:|| .||:
Mouse   267 VLAQSYKENEIKENIQVFEFELPSEDMKILDSLDRNLRYAPAPFGEGHPEYPF-SDEF 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_001261716.1	ARA1	38..316	CDD:223729	145/282 (51%)
		Tas	45..>248	CDD:223739	116/211 (55%)
Akr1c19	NP_001013807.2	ARA1	8..307	CDD:223729	150/299 (50%)
		Tas	11..310	CDD:223739	151/302 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	1	1.100	-	-	O	PTHR11732
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.930