Protein Alignment Akr1B and Akr1c12

DIOPT Version :9

• Sequence 1: NP_001261716.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_001014262.3
• Gene: Akr1c12 / 364773
• RGDID: 1359406
• Length: 323
• Species: Rattus norvegicus
• Alignment Length: 321
• Identity: 141/321 - (43%)
• Similarity: 208/321 - (64%)
• Gaps: 10/321 - (3%)

  Fly    39 KVVCL---DGNEIPVIGLGTFNS---PKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAK 97
            |:.|:   ||:.||.:|.||:..   ||.:..||..:|||.||||||.|..||.|:|:|..:::|
  Rat     4 KLHCVKLNDGHFIPALGFGTYKPKEVPKSKSLEAAHLAIDVGYRHIDTASAYQVEEEIGQAIQSK 68

  Fly    98 IKEGVVKREDLFITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDK 162
            ||.|||||:|:|||:|||.:..|.::|:.|||.:|.:|:|.|:||:|||:|:..|...|..|.|:
  Rat    69 IKAGVVKRKDMFITTKLWCSCFRTEMVRPALEKSLKNLQLDYVDLFLIHYPVPIKSSVDESPLDE 133

  Fly   163 DGKTLYSPVDYVDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATI--PPVTNQIECHPYLT 225
            .||.|...||:.|||:.:||..:.||||||||||||.:|:||:|....:  .||.||:|||.||.
  Rat   134 KGKFLLDTVDFCDTWEMLEKCKDAGLVKSIGVSNFNHKQLERLLNKPGLKYKPVCNQVECHLYLN 198

  Fly   226 QKKLIDFCKSKDITITAYSPLGSPN-RPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQR 289
            |.||:|:||||||.:.||..||:.. :.|.....||:|::..:.::|.|.|::|..|.:||..||
  Rat   199 QSKLLDYCKSKDIVLVAYGALGTQRYKEWVDQNSPVLLDDPILCDVAKKNKRSPALIALRYLFQR 263

  Fly   290 ANIVIPKSVTKDRIESNFQVFDFELTPEEIEIIESFECNGRLVPLLNQYGHPHHPFEKDEY 350
            ..:.:.:|..::.:..|.|||:|:|:||:::.::....|.|.:.......||.:|| .:||
  Rat   264 GVVPLAQSFKENEMRENLQVFEFQLSPEDMKTLDGLNKNFRYLSAEFLADHPEYPF-SEEY 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_001261716.1	ARA1	38..316	CDD:223729	131/285 (46%)
		Tas	45..>248	CDD:223739	107/207 (52%)
Akr1c12	NP_001014262.3	ARA1	8..305	CDD:223729	132/296 (45%)
		Tas	16..297	CDD:223739	129/280 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11732
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.930