Protein Alignment Akr1B and Akr1c13

DIOPT Version :9

• Sequence 1: NP_001261716.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: XP_006254252.1
• Gene: Akr1c13 / 361266
• RGDID: 1308232
• Length: 371
• Species: Rattus norvegicus
• Alignment Length: 367
• Identity: 155/367 - (42%)
• Similarity: 221/367 - (60%)
• Gaps: 27/367 - (7%)

  Fly     4 LMKIQLVRPVFRITLRNYGKPERFMWCQKEYARAPKV-----------------VCLDGNEIPVI 51
            |.|||....|.:|   ::|:.|...:.|:...|...:                 .||..   |.:
  Rat    12 LFKIQSSEYVNQI---SFGQAEYVAYLQRAEGRMSPLSEPEQAAGFLQVMRHCSCCLCS---PGV 70

  Fly    52 GLGTFNSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEGVVKREDLFITSKLWN 116
            .......||.:..||..:||||||||||.||.||.|:|:|..:::|||.|||||||:|||:|||.
  Rat    71 SASYKLVPKSKSLEAAHLAIDAGYRHIDTAYAYQIEEEIGQAIQSKIKAGVVKREDMFITTKLWC 135

  Fly   117 TFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDGKTLYSPVDYVDTWKAME 181
            |..||:|||.|||.:|.:|:|.|.|||::|:|:..|.|.:.||.|:.||:|...||:.|||:.:|
  Rat   136 TCFRPELVKPALEKSLKNLQLDYADLYIMHYPVPMKSGDNDFPVDEKGKSLLDTVDFCDTWEMLE 200

  Fly   182 KLVEEGLVKSIGVSNFNRRQIERVLEVATI--PPVTNQIECHPYLTQKKLIDFCKSKDITITAYS 244
            |..:.||||||||||||.:|:||:|....:  .||.||:|||.||.|.||:|:||||||.:.||.
  Rat   201 KCKDAGLVKSIGVSNFNHKQLERLLNKPGLKYKPVCNQVECHLYLNQSKLLDYCKSKDIVLVAYG 265

  Fly   245 PLGSPN-RPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIPKSVTKDRIESNFQ 308
            .||:.. :.|.....||:|.:..:.::|.|.|::|..|.:||.|||..:.:.:|..::.:..|.|
  Rat   266 ALGTQRYKEWVDQNSPVLLNDPVLCDVAKKNKRSPALIALRYLVQRGVVPLAQSFKENEMRENLQ 330

  Fly   309 VFDFELTPEEIEIIESFECNGRLVPLLNQYGHPHHPFEKDEY 350
            ||||:|:||:::.::....|.|.:......|||.:|| .:||
  Rat   331 VFDFQLSPEDMKTLDGLNKNFRYLSAEFLAGHPEYPF-SEEY 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_001261716.1	ARA1	38..316	CDD:223729	134/297 (45%)
		Tas	45..>248	CDD:223739	109/204 (53%)
Akr1c13	XP_006254252.1	Tas	77..345	CDD:223739	133/267 (50%)
		ARA1	89..353	CDD:223729	130/263 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11732
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.930