Protein Alignment Akr1B and Akr1c1

DIOPT Version :10

• Sequence 1: NP_729726.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_001028869.1
• Gene: Akr1c1 / 307092
• RGDID: 1306847
• Length: 323
• Species: Rattus norvegicus
• Alignment Length: 315
• Identity: 158/315 - (50%)
• Similarity: 211/315 - (66%)
• Gaps: 11/315 - (3%)

  Fly    44 DGNEIPVIGLGTF---NSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEGVVKR 105
            ||:.|||:|.||:   ..||.:..||.|:|||||:||||.|.|||||.|||..:.:||.:|.|||
  Rat    12 DGHFIPVLGFGTYAPREVPKSKALEATKIAIDAGFRHIDSAAVYQNEKEVGLAIRSKIADGTVKR 76

  Fly   106 EDLFITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDGKTLYSP 170
            ||:|.|||:|.||:.|:.|:..||.:|..|:|:|:||||||:||..|...||...|::.|.|:..
  Rat    77 EDIFYTSKVWCTFNHPERVQVCLEQSLKQLQLEYVDLYLIHFPMALKPEEDLKAKDENEKLLFDV 141

  Fly   171 VDYVDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATIP--PVTNQIECHPYLTQKKLIDFC 233
            ||..||||||||..:.||.||||||||||||:|::|....:.  ||.||:||||||.|:||:|||
  Rat   142 VDICDTWKAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKHRPVCNQVECHPYLNQRKLLDFC 206

  Fly   234 KSKDITITAYSPLGSPNRPWAKAGD---PVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIP 295
            |||||.:.|||.|||...  .:..|   ||:|.:..:..||.|...||..|.:|||::|..:|:.
  Rat   207 KSKDIVLVAYSALGSHRE--TRCVDKSLPVLLADPVLCAIAKKYNWTPALIALRYQLERGVVVLA 269

  Fly   296 KSVTKDRIESNFQVFDFELTPEEIEIIESFECNGRLVPLLKDAGTHKYYPFHDEY 350
            ||.|:.||:.|.|||:|:||.|::::::....|.|.:...:..| |..:||.|||
  Rat   270 KSFTEKRIKENMQVFEFQLTSEDMKVLDGLNKNIRYMSGSRFQG-HPDFPFLDEY 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_729726.1	AKR_SF	45..350	CDD:444925	155/312 (50%)
Akr1c1	NP_001028869.1	AKR_AKR1C1-35	6..308	CDD:381334	151/297 (51%)