Protein Alignment Akr1B and Akr1e2

DIOPT Version :9

• Sequence 1: NP_001261716.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_001008343.1
• Gene: Akr1e2 / 307091
• RGDID: 1309599
• Length: 301
• Species: Rattus norvegicus
• Alignment Length: 303
• Identity: 166/303 - (54%)
• Similarity: 216/303 - (71%)
• Gaps: 10/303 - (3%)

  Fly    46 NEIPVIGLGTFNSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEGVVKREDLFI 110
            ::||.:||||:.:..|:||:||||||:.||||.||||:|.||.|||.|::.|||||||||::|||
  Rat     2 HQIPTVGLGTWKASPGEVTDAVKVAINLGYRHFDCAYLYHNESEVGMGIKEKIKEGVVKRDELFI 66

  Fly   111 TSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDGKTLYSPVDYVD 175
            .||||.|:|:..|||:|..|||.:|.|.||||||||||||:|.|....|.|:.||.:.|...::|
  Rat    67 VSKLWCTYHKQSLVKTACINTLEALNLDYLDLYLIHWPMGFKPGDKDIPLDRSGKVIPSHTSFLD 131

  Fly   176 TWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEV--ATIPPVTNQIECHPYLTQKKLIDFCKSKDI 238
            ||:|||.||.|||||:|||||||..|::|:|..  ..|.|:||||||||||.||.|||||..:::
  Rat   132 TWEAMEDLVIEGLVKNIGVSNFNHEQLDRLLNKPGLRIKPITNQIECHPYLNQKSLIDFCHGRNV 196

  Fly   239 TITAYSPLGSPNRPWAKAGDPV-ILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIPKSVTKDR 302
            ::|||.|||.       :.|.| ::::..|::||.|..|:|.|||||:|:||..|||||||...|
  Rat   197 SVTAYRPLGG-------SRDGVHLMDDIVIRKIAKKHGKSPAQILIRFQIQRNLIVIPKSVNPSR 254

  Fly   303 IESNFQVFDFELTPEEIEIIESFECNGRLVPLLNQYGHPHHPF 345
            |..|.||||||||.:::|.:.|.:.|.||....:...|..:||
  Rat   255 IRENIQVFDFELTEKDMEELLSLDKNLRLATFPSTENHKDYPF 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_001261716.1	ARA1	38..316	CDD:223729	157/272 (58%)
		Tas	45..>248	CDD:223739	123/203 (61%)
Akr1e2	NP_001008343.1	Tas	4..287	CDD:223739	163/289 (56%)
		ARA1	4..282	CDD:223729	161/284 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348825
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	374	1.000	Inparanoid score	I2032
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	1	1.000	-	-		otm45342
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	1	1.100	-	-	LDO	PTHR11732
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.770