Protein Alignment Akr1B and Akr1b10

DIOPT Version :9

• Sequence 1: NP_001261716.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_001013102.1
• Gene: Akr1b10 / 296972
• RGDID: 1308277
• Length: 316
• Species: Rattus norvegicus
• Alignment Length: 304
• Identity: 175/304 - (57%)
• Similarity: 216/304 - (71%)
• Gaps: 2/304 - (0%)

  Fly    47 EIPVIGLGTFNSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEGVVKREDLFIT 111
            ::|::||||:.||..:|.||||.||||||||.|||||||||.|||:.::.||||..|:||||||.
  Rat    12 KMPIVGLGTWKSPPDKVKEAVKAAIDAGYRHFDCAYVYQNESEVGEAIQEKIKEKAVRREDLFIV 76

  Fly   112 SKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDGKTLYSPVDYVDT 176
            ||||.||....|||.|.:.||..|||.||||||||||.|::.|....|||..|..|.|...::|.
  Rat    77 SKLWPTFFEKSLVKKAFQKTLLDLKLDYLDLYLIHWPQGFQSGNVFLPTDDKGNVLTSKYTFLDA 141

  Fly   177 WKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATI--PPVTNQIECHPYLTQKKLIDFCKSKDIT 239
            |:.||:||::||||::||||||..||||:|....:  .|||||:||||||||:|||.:|.||.|.
  Rat   142 WEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLIQYCHSKGIV 206

  Fly   240 ITAYSPLGSPNRPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIPKSVTKDRIE 304
            :|||||||||:||.||..|||:||..||||||:|.|||..|:|||:.::|...|||||||..||:
  Rat   207 VTAYSPLGSPDRPSAKPEDPVLLEIPKIKEIASKHKKTAAQVLIRFHIERNVAVIPKSVTPSRIQ 271

  Fly   305 SNFQVFDFELTPEEIEIIESFECNGRLVPLLNQYGHPHHPFEKD 348
            .|.|||||:|:.|::..|.||..|.|...|.....:...||..:
  Rat   272 ENIQVFDFQLSEEDMAAILSFNRNWRACGLFAASRNEDFPFHSE 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_001261716.1	ARA1	38..316	CDD:223729	166/270 (61%)
		Tas	45..>248	CDD:223739	123/202 (61%)
Akr1b10	NP_001013102.1	AKR_AKR1B1-19	10..316	CDD:381333	175/304 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	356	1.000	Domainoid score	I948
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	374	1.000	Inparanoid score	I2032
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	1	1.000	-	-		otm45342
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	1	1.100	-	-	O	PTHR11732
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.880