Protein Alignment Akr1B and Akr1c2

DIOPT Version :10

• Sequence 1: NP_729726.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_001427047.1
• Gene: Akr1c2 / 291283
• RGDID: 1311841
• Length: 323
• Species: Rattus norvegicus
• Alignment Length: 317
• Identity: 145/317 - (45%)
• Similarity: 201/317 - (63%)
• Gaps: 15/317 - (4%)

  Fly    44 DGNEIPVIGLGT---FNSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEGVVKR 105
            ||:.|||:|.||   ...||.:..|..|:|||||:.|.|.|:||..||.||:.:..||..|..:|
  Rat    12 DGHFIPVLGFGTAMPSELPKSKAKEVTKIAIDAGFHHFDSAFVYNTEDHVGEAIREKIANGTTRR 76

  Fly   106 EDLFITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDGKTLYSP 170
            ||:|.|||||.|...|:||:|:||.:|..|:|.|:||||||:||..|.|.:.||.|:.||.|:..
  Rat    77 EDIFYTSKLWCTSLHPELVRSSLECSLKKLQLDYVDLYLIHFPMALKPGDENFPVDEHGKLLFDT 141

  Fly   171 VDYVDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATI--PPVTNQIECHPYLTQKKLIDFC 233
            ||...||:||||..:.||.||||||||||||:|::|....:  .||.||:|||.||.|.||:|||
  Rat   142 VDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKYKPVCNQVECHLYLNQMKLLDFC 206

  Fly   234 KSKDITITAYSPLGSPN-RPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIPKS 297
            |:..|.:.||..||:.. ..|.....||:|.|..:..:|.|..:||..|.:|:|:||..:|:..|
  Rat   207 KTNGIILVAYGVLGTQRYNGWVDQNSPVLLNEPVLSSMAKKYNQTPALIALRHQLQRGIVVLNTS 271

  Fly   298 VTKDRIESNFQVFDFELTPEEIEIIESFECNGRLVPLLKDAG----THKYYPFHDEY 350
            :.::||:.|.:||:|:|:||::::::....|.|.:     ||    .|..:||.|||
  Rat   272 LKEERIKENMKVFEFQLSPEDMKVLDDLNRNLRYI-----AGGIFEGHPNFPFLDEY 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_729726.1	AKR_SF	45..350	CDD:444925	142/314 (45%)
Akr1c2	NP_001427047.1	None