Protein Alignment Akr1B and Akr1c2

DIOPT Version :9

• Sequence 1: NP_001261716.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: XP_006254245.1
• Gene: Akr1c2 / 291283
• RGDID: 1311841
• Length: 323
• Species: Rattus norvegicus
• Alignment Length: 313
• Identity: 145/313 - (46%)
• Similarity: 201/313 - (64%)
• Gaps: 7/313 - (2%)

  Fly    44 DGNEIPVIGLGT---FNSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEGVVKR 105
            ||:.|||:|.||   ...||.:..|..|:|||||:.|.|.|:||..||.||:.:..||..|..:|
  Rat    12 DGHFIPVLGFGTAMPSELPKSKAKEVTKIAIDAGFHHFDSAFVYNTEDHVGEAIREKIANGTTRR 76

  Fly   106 EDLFITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDGKTLYSP 170
            ||:|.|||||.|...|:||:|:||.:|..|:|.|:||||||:||..|.|.:.||.|:.||.|:..
  Rat    77 EDIFYTSKLWCTSLHPELVRSSLECSLKKLQLDYVDLYLIHFPMALKPGDENFPVDEHGKLLFDT 141

  Fly   171 VDYVDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATI--PPVTNQIECHPYLTQKKLIDFC 233
            ||...||:||||..:.||.||||||||||||:|::|....:  .||.||:|||.||.|.||:|||
  Rat   142 VDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKYKPVCNQVECHLYLNQMKLLDFC 206

  Fly   234 KSKDITITAYSPLGSPN-RPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIPKS 297
            |:..|.:.||..||:.. ..|.....||:|.|..:..:|.|..:||..|.:|:|:||..:|:..|
  Rat   207 KTNGIILVAYGVLGTQRYNGWVDQNSPVLLNEPVLSSMAKKYNQTPALIALRHQLQRGIVVLNTS 271

  Fly   298 VTKDRIESNFQVFDFELTPEEIEIIESFECNGRLVPLLNQYGHPHHPFEKDEY 350
            :.::||:.|.:||:|:|:||::::::....|.|.:......|||:.|| .|||
  Rat   272 LKEERIKENMKVFEFQLSPEDMKVLDDLNRNLRYIAGGIFEGHPNFPF-LDEY 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_001261716.1	ARA1	38..316	CDD:223729	133/277 (48%)
		Tas	45..>248	CDD:223739	108/207 (52%)
Akr1c2	XP_006254245.1	AKR_AKR1C1-35	6..308	CDD:381334	137/295 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11732
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.930