Protein Alignment Akr1B and Akr1b1

DIOPT Version :10

• Sequence 1: NP_729726.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_036630.1
• Gene: Akr1b1 / 24192
• RGDID: 2092
• Length: 316
• Species: Rattus norvegicus
• Alignment Length: 308
• Identity: 189/308 - (61%)
• Similarity: 229/308 - (74%)
• Gaps: 3/308 - (0%)

  Fly    44 DGNEIPVIGLGTFNSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEGVVKREDL 108
            :|.::|.:||||:.||.||||||||||||.||||||||.|||||.|||..::.|:||.||||:||
  Rat     9 NGTKMPTLGLGTWKSPPGQVTEAVKVAIDMGYRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQDL 73

  Fly   109 FITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDGKTLYSPVDY 173
            ||.||||.|||...:||.|.:.|||.|:|.||||||||||.|:|.|.|.||.|..|..:.|..|:
  Rat    74 FIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDASGNVIPSDTDF 138

  Fly   174 VDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATI--PPVTNQIECHPYLTQKKLIDFCKSK 236
            ||||.|||:||:|||||:|||||||..||||:|....:  .|..|||||||||||:|||::|..|
  Rat   139 VDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHCK 203

  Fly   237 DITITAYSPLGSPNRPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIPKSVTKD 301
            .|.:|||||||||:|||||..||.:||:.:|||||||..||..|:|||:.:||..:|||||||..
  Rat   204 GIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKEIAAKYNKTTAQVLIRFPIQRNLVVIPKSVTPA 268

  Fly   302 RIESNFQVFDFELTPEEIEIIESFECNGRLVPLLKDAGTHKYYPFHDE 349
            ||..||:||||||:.|::..:.|:..|.|:..|:..| .||.||||.|
  Rat   269 RIAENFKVFDFELSNEDMATLLSYNRNWRVCALMSCA-KHKDYPFHAE 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_729726.1	AKR_SF	45..350	CDD:444925	189/307 (62%)
Akr1b1	NP_036630.1	AKR_AKR1B1-19	10..315	CDD:381333	188/305 (62%)