Protein Alignment Akr1B and AKR7A3

DIOPT Version :10

• Sequence 1: NP_729726.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: XP_011539348.1
• Gene: AKR7A3 / 22977
• HGNCID: 390
• Length: 375
• Species: Homo sapiens
• Alignment Length: 212
• Identity: 51/212 - (24%)
• Similarity: 87/212 - (41%)
• Gaps: 70/212 - (33%)

  Fly    63 VTEAVKVAIDAGYRHIDCAYVY---QNEDEVG------DGVEAKIKEGVVKREDLFITSK---LW 115
            ||.|.   ::.|:..||.|:||   |:|..:|      .|.:.::|          |.:|   |:
Human    31 VTRAF---LERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVK----------IDTKAIPLF 82

  Fly   116 NTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDGKTLYSPVDYVDTWKAM 180
            ....:||.::..||.:|..|:...:||:.:|.|              |..|   ||:  :|.:|.
Human    83 GNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMP--------------DHST---PVE--ETLRAC 128

  Fly   181 EKLVEEGLVKSIGVSNFNRRQIERVLEVAT--------IPPV--------TNQIECHPYLTQKKL 229
            .:|.:||....:|:||:...:   |.|:.|        :|.|        |.|:|       .:|
Human   129 HQLHQEGKFVELGLSNYAAWE---VAEICTLCKSNGWILPTVYQGMYNAITRQVE-------TEL 183

  Fly   230 IDFCKSKDITITAYSPL 246
            ....:...:...|::||
Human   184 FPCLRHFGLRFYAFNPL 200

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_729726.1	AKR_SF	45..350	CDD:444925	51/212 (24%)
AKR7A3	XP_011539348.1	AKR_AKR7A1-5	10..281	CDD:381301	51/212 (24%)