Protein Alignment Akr1B and Akr1d1

DIOPT Version :10

• Sequence 1: NP_729726.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: XP_017176967.1
• Gene: Akr1d1 / 208665
• MGIID: 2384785
• Length: 328
• Species: Mus musculus
• Alignment Length: 305
• Identity: 145/305 - (47%)
• Similarity: 196/305 - (64%)
• Gaps: 6/305 - (1%)

  Fly    18 LRNYGKPERFMWCQKEYARAPKVVCLDGNEIPVIGLGTFNSPK---GQVTEAVKVAIDAGYRHID 79
            ::|:.:..||.......|...::...|||.||:|||||::.|:   |:...|||.|||.||||||
Mouse     6 VQNHPRSFRFFSTMNLSAAHHQISLSDGNNIPLIGLGTYSDPRPVPGKTYVAVKTAIDEGYRHID 70

  Fly    80 CAYVYQNEDEVGDGVEAKIKEGVVKREDLFITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYL 144
            .||||.||.|||:.:..||.||.||||::|...|||||.|.|.:|..|||.||.:|||.|:|||:
Mouse    71 GAYVYHNEHEVGEAIREKIAEGKVKREEIFYCGKLWNTEHVPSMVLPALERTLKALKLDYIDLYI 135

  Fly   145 IHWPMGYKEGCDLFPTDKDGKTLYSPVDYVDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVA 209
            |..||.:|.|.:::|.|::|:.:|...:...||:|:|...:.|||||:|||||||||:|.:|...
Mouse   136 IELPMAFKPGKEIYPRDENGRIIYDKTNLCATWEALEACKDAGLVKSLGVSNFNRRQLELILNKP 200

  Fly   210 TI--PPVTNQIECHPYLTQKKLIDFCKSKDITITAYSPLGSPNRP-WAKAGDPVILEEAKIKEIA 271
            .:  .|||||:|||||.||.||:.||:..||.|.|:||||:...| |.....|.:|.:..:..:.
Mouse   201 GLKYKPVTNQVECHPYFTQTKLLKFCQQHDIVIVAHSPLGTCRNPSWVNVSSPPLLNDELLTSLG 265

  Fly   272 AKKKKTPGQILIRYQVQRANIVIPKSVTKDRIESNFQVFDFELTP 316
            .|..||..||::|:.:||..:|||||.|.:||:.||||....|.|
Mouse   266 KKYNKTQAQIVLRFNIQRGIVVIPKSFTPERIKENFQVQCAPLPP 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_729726.1	AKR_SF	45..350	CDD:444925	140/278 (50%)
Akr1d1	XP_017176967.1	AKR_SF	33..303	CDD:444925	136/269 (51%)