Protein Alignment Akr1B and K07C5.2

DIOPT Version :10

• Sequence 1: NP_729726.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_505658.1
• Gene: K07C5.2 / 187089
• WormBaseID: WBGene00010625
• Length: 301
• Species: Caenorhabditis elegans
• Alignment Length: 297
• Identity: 98/297 - (32%)
• Similarity: 152/297 - (51%)
• Gaps: 27/297 - (9%)

  Fly    44 DGNEIPVIGLGTFNSPKGQ-VTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEGVVKRED 107
            ||.|:|.||||.......| :..:::.|:.:|||..|.|.:|:||..:|:.::..:.:..:.|||
 Worm    16 DGYEMPKIGLGISRIETQQDLDVSIEAALKSGYRQFDTANLYKNETFLGNSLKKYLPQFGLTRED 80

  Fly   108 LFITSKL----WNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEG-CDLFPTDKDGKTL 167
            :|||:|:    .||...   .:..|.|:|::|:..|:||.|||:|.....| .|.:..:|..:.:
 Worm    81 VFITTKVRTLNENTVEE---TEKQLANSLATLQTDYVDLLLIHYPRDRDTGNDDDYEINKSRRKI 142

  Fly   168 YSPVDYVDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATIPPVTNQIECHPYLTQKKLIDF 232
                    .|:.:||..|.|.|:||||||:....:..:.|.|.|.||.||.|..||||:..|..|
 Worm   143 --------VWQTLEKAKESGRVRSIGVSNYEVYHLVEMFEYAKIRPVLNQYEYQPYLTRPTLKKF 199

  Fly   233 CKSKDITITAYSPLGSPNRPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIPKS 297
            |...:|.:.:||.|     .|   ||..||:|..:.::..|..:||..||..:.......:||||
 Worm   200 CDLNNIVVQSYSSL-----CW---GDKEILQEKPLVDLCQKYNQTPQAILYAFAHCSNTSMIPKS 256

  Fly   298 VTKDRIESNF-QVFDFELTPEEIEIIESFECNGRLVP 333
            .|..||..|. .....:||.:|::.:.|.: .|:..|
 Worm   257 ATPSRIHDNLHNTIKIKLTEDELKSLRSLD-KGKSFP 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_729726.1	AKR_SF	45..350	CDD:444925	97/296 (33%)
K07C5.2	NP_505658.1	AKR_AKR1-5-like	20..282	CDD:381297	92/280 (33%)