Protein Alignment Akr1B and F53F1.3

DIOPT Version :10

• Sequence 1: NP_729726.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_506323.1
• Gene: F53F1.3 / 186169
• WormBaseID: WBGene00009981
• Length: 283
• Species: Caenorhabditis elegans
• Alignment Length: 288
• Identity: 97/288 - (33%)
• Similarity: 150/288 - (52%)
• Gaps: 32/288 - (11%)

  Fly    45 GNEIPVIGLGTFNSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEGVVKREDLF 109
            |.:.|:|||||:.....||...:..|:.||||..|.|.||.||.|:||.:|..:.:..:||||:|
 Worm     8 GYDCPLIGLGTYKIIGDQVLPVLDAALTAGYRLFDTAKVYNNEKEIGDALEILLPKHNLKREDIF 72

  Fly   110 ITSKLW-NTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKD--GKTLYSPV 171
            ||:|:. ||...   ||..::.:||.||..|:|:||||:|..:..|      |:|  .|||
 Worm    73 ITTKMHPNTVEN---VKKLVDESLSLLKTSYIDMYLIHYPKSFDYG------DQDPMNKTL---- 124

  Fly   172 DYVDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVA-TIPPVTNQIECHPYLTQKKLIDFCKS 235
             .:.||..:.:....|.::|:|||:|..|.:|.:.::. ..||..||:|.||:.|:::|.::|||
 Worm   125 -RIATWNDLWECKNAGKIRSVGVSSFEIRHLEELKDLGKNFPPCCNQVEYHPHFTREELKNYCKS 188

  Fly   236 KDITITAYSPLGSPNRPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIPKSVTK 300
            :.|...|:|.|...|.        .:|....|..:|.|.......:|:.:...:...:||||...
 Worm   189 EGIFFQAFSSLARHNE--------TLLSSEIITRLAEKYHVPKTTVLLSWATSQKVGIIPKSTNP 245

  Fly   301 DRIESNFQVFDFELTPEEIEIIESFECN 328
            :|:..|.:....|  .||::.|    ||
 Worm   246 ERLAQNLKTVLLE--EEEVKKI----CN 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_729726.1	AKR_SF	45..350	CDD:444925	97/288 (34%)
F53F1.3	NP_506323.1	AKR_AKR1-5-like	12..265	CDD:381297	93/276 (34%)