Protein Alignment Akr1B and C07D8.6

DIOPT Version :10

• Sequence 1: NP_729726.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_509242.1
• Gene: C07D8.6 / 180997
• WormBaseID: WBGene00015565
• Length: 317
• Species: Caenorhabditis elegans
• Alignment Length: 305
• Identity: 124/305 - (40%)
• Similarity: 182/305 - (59%)
• Gaps: 25/305 - (8%)

  Fly    44 DGNEIPVIGLGTFNSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEGVVKREDL 108
            :|.|:|||||||:.|...:|..|||.|:.||||.||.|.|||||:.:|..::..::|||||||:|
 Worm    12 NGVEMPVIGLGTWQSSPAEVITAVKTAVKAGYRLIDTASVYQNEEAIGTAIKELLEEGVVKREEL 76

  Fly   109 FITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDGKTLYSPVDY 173
            |||:|.|.....|..::..|..:|..|:|:|:||||.|.|..:        .|...:.:.|||:
 Worm    77 FITTKAWTHELAPGKLEGGLRESLKKLQLEYVDLYLAHMPAAF--------NDDMSEHIASPVE- 132

  Fly   174 VDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATIPPVTNQIECHPYLTQKKLIDFCKSKDI 238
             |.|:..:.:.:.||.|::||||:|..||.|.|.:...|...:|:|.|.|..|...:||||..:|
 Worm   133 -DVWRQFDAVYKAGLAKAVGVSNWNNDQISRALALGLTPVHNSQVELHLYFPQHDHVDFCKKHNI 196

  Fly   239 TITAYSPLGSPNR-----------PWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANI 292
            ::|:|:.||||.|           .||.|  |..|::..:..:|.|..|||.|:|:||.:.|...
 Worm   197 SVTSYATLGSPGRVNFTLPTGQKLDWAPA--PSDLQDQNVLALAEKTHKTPAQVLLRYALDRGCA 259

  Fly   293 VIPKSVTKDRIESNFQVFDFELTPEEIEIIESFECNGRLVPLLKD 337
            ::|||:.::||:.||:||||.||.|:|..:|..:.:.||  .|:|
 Worm   260 ILPKSIQENRIKENFEVFDFSLTEEDIAKLEESKNSQRL--FLQD 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_729726.1	AKR_SF	45..350	CDD:444925	124/304 (41%)
C07D8.6	NP_509242.1	AKR_AKR1G1_CeAKR	5..301	CDD:381380	122/302 (40%)