Protein Alignment Akr1B and F53F1.2

DIOPT Version :10

• Sequence 1: NP_729726.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_001379192.1
• Gene: F53F1.2 / 179821
• WormBaseID: WBGene00009980
• Length: 297
• Species: Caenorhabditis elegans
• Alignment Length: 300
• Identity: 93/300 - (31%)
• Similarity: 155/300 - (51%)
• Gaps: 33/300 - (11%)

  Fly    45 GNEIPVIGLGTFNSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEGVVKREDLF 109
            |..||.:|.||:......|..|:..|:.||||..|.|..|.||.|:|:.::..:.:..:.|.|:|
 Worm    18 GYNIPFVGFGTYKVTGENVPPAIDAALTAGYRMFDTAKYYLNEKELGEALKILLPKHGLSRSDVF 82

  Fly   110 ITSKLW-NTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDGKTL----YS 169
            :|||.: .:.:..:..:..:|.:|.||:..|:|:||:|:|.         |.|.|...:    |.
 Worm    83 LTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYPK---------PNDSDNDDVNNAEYR 138

  Fly   170 PVDYVDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATIPPVTNQIECHPYLTQKKLIDFCK 234
            .:.|    :.:|:....|.|:||||||:....:|.:...|.:||..||:|.||:..:..|..:||
 Worm   139 KIAY----EVLEEAKAAGKVRSIGVSNYEIVHLEELKTYAKVPPCANQLEYHPHFARIPLQKYCK 199

  Fly   235 SKDITITAYSPLGSPNRPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIPKSVT 299
            .|:|...|:|.|.        ..:|.::|:..:.|:|.|...:...:|:.:.:::...::|||||
 Worm   200 EKNIFFQAFSSLA--------RHEPKLIEDPVVVELAKKHNTSVPLVLLAWALRQNVGIVPKSVT 256

  Fly   300 KDRIESNFQVFDFELTPEEIEIIESFE-------CNGRLV 332
            ..||..||:|.|..||||:|:.:.:.:       |.|.||
 Worm   257 PSRIVENFKVIDIALTPEDIQSLTALDRGQHYIRCTGWLV 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_729726.1	AKR_SF	45..350	CDD:444925	92/299 (31%)
F53F1.2	NP_001379192.1	AKR_AKR1-5-like	21..279	CDD:381297	88/278 (32%)