Protein Alignment Akr1B and Y39G8B.1

DIOPT Version :9

• Sequence 1: NP_001261716.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_001370070.1
• Gene: Y39G8B.1 / 175047
• WormBaseID: WBGene00012722
• Length: 316
• Species: Caenorhabditis elegans
• Alignment Length: 303
• Identity: 154/303 - (50%)
• Similarity: 195/303 - (64%)
• Gaps: 2/303 - (0%)

  Fly    45 GNEIPVIGLGTFNSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEGVVKREDLF 109
            |..||.|||||:.|..|:|..|:|.|:.|||||||||:||||:.|||:.::..:.||.||||:||
 Worm    10 GYSIPAIGLGTWQSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQKEVGEALKEILDEGKVKREELF 74

  Fly   110 ITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDGKTLYSPVDYV 174
            ||||:|||||........::..||.|:|.|:||.|||||.||.||.:|||..::||..||.|||:
 Worm    75 ITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHWPQGYAEGAELFPAGENGKMRYSDVDYL 139

  Fly   175 DTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATIPPVTNQIECHPYLTQKKLIDFCKSKDIT 239
            :||||.|...:.|..:|||:|||...||:||.:.|.:.|...|:|.|||.||.||.:|||.|.|.
 Worm   140 ETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVWDAAEVKPACLQVELHPYFTQVKLREFCKEKGIV 204

  Fly   240 ITAYSPLGSPNRP-WAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIPKSVTKDRI 303
            :..|||||:|... :.|.|||.:|....:..||....|||.||::|:.|......||||||..||
 Worm   205 VVGYSPLGNPGSAFFRKDGDPNVLTNEVVAGIAKAHGKTPAQIILRWFVDSGLSAIPKSVTPQRI 269

  Fly   304 ESNFQVFDFELTPEEIEIIESFECNGRLVPLLNQYG-HPHHPF 345
            ..|..||||:||.|||..|:....|.|:|.|..:.| |||.||
 Worm   270 SENLAVFDFQLTAEEISKIDGINKNWRIVDLSQRDGDHPHCPF 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_001261716.1	ARA1	38..316	CDD:223729	139/271 (51%)
		Tas	45..>248	CDD:223739	109/202 (54%)
Y39G8B.1	NP_001370070.1	AKR_SF	7..305	CDD:412396	148/294 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166070
Domainoid	1	1.000	284	1.000	Domainoid score	I862
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	304	1.000	Inparanoid score	I1599
Isobase	1	0.950	-	0	Normalized mean entropy	S875
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	1	1.000	-	-		mtm8417
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	1	1.100	-	-	LDO	PTHR11732
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1770
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.890