DRSC/TRiP Functional Genomics Resources

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Protein Alignment Akr1B and Gclm

DIOPT Version :9

Sequence 1:NP_001261716.1 Gene:Akr1B / 39304 FlyBaseID:FBgn0086254 Length:350 Species:Drosophila melanogaster
Sequence 2:NP_032155.1 Gene:Gclm / 14630 MGIID:104995 Length:274 Species:Mus musculus


Alignment Length:256 Identity:59/256 - (23%)
Similarity:105/256 - (41%) Gaps:69/256 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    79 DCAYVYQNE----------DEVGDGVEAKIKEGVVK-----REDLFITSKLWNT-FHRPDLVKSA 127
            ||.....||          .|..|.:|..:...|.|     ||::.:::||:.. .:.....:||
Mouse    45 DCIQKTLNEWSSQISPDLVREFPDVLECTMSHAVEKINPDEREEMKVSAKLFIVGSNSSSSTRSA 109

  Fly   128 LENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDGKTLYSPVDYVDT-WKAMEKLVEEGLVKS 191
            ::...|.|.:..||..::           ..|..:||..|  .::::.. |:.:|.||:...:.:
Mouse   110 VDMACSVLGVAQLDSVIM-----------ASPPIEDGVNL--SLEHLQPYWEELENLVQSKKIVA 161

  Fly   192 IGVSNFNRRQIERVLEVATIPPVTNQIE----C--HPYLTQKKLIDFCKSKDITITAYSPLGSPN 250
            ||.|:.::.|:|::.:.|.:.|.:||:.    |  .|.||.     |.|..||.:..::      
Mouse   162 IGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTA-----FAKQFDIQLLTHN------ 215

  Fly   251 RPWAKAGDP-VILEEAKIKEIAAKKKKTPG--------QILIRYQVQRANIVIPKSVTKDR 302
                   || .:|.||..:|  |.::..|.        ..|:||.|    ||..:.:.|.:
Mouse   216 -------DPKELLSEASFQE--ALQESIPDIEAQDWVPLWLLRYSV----IVKSRGIIKSK 263

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Akr1BNP_001261716.1 ARA1 38..316 CDD:223729 59/256 (23%)
Tas 45..>248 CDD:223739 44/191 (23%)
GclmNP_032155.1 AKR_SF <109..>211 CDD:412396 30/119 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0656
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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