Protein Alignment Akr1B and Akr1b8

DIOPT Version :9

• Sequence 1: NP_001261716.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_032038.1
• Gene: Akr1b8 / 14187
• MGIID: 107673
• Length: 316
• Species: Mus musculus
• Alignment Length: 304
• Identity: 173/304 - (56%)
• Similarity: 221/304 - (72%)
• Gaps: 2/304 - (0%)

  Fly    47 EIPVIGLGTFNSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEGVVKREDLFIT 111
            ::|::||||:.||..||.||||.|||||||||||||.|.||:|||:.::.||||..|:||||||.
Mouse    12 KMPIVGLGTWKSPPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQEKIKEKAVQREDLFIV 76

  Fly   112 SKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDGKTLYSPVDYVDT 176
            ||||.|.....|:|.|.:.||:.|||.||||||||||.|.:.|.:|||.|..|:.|.|...:::.
Mouse    77 SKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKELFPKDDQGRILTSKTTFLEA 141

  Fly   177 WKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATI--PPVTNQIECHPYLTQKKLIDFCKSKDIT 239
            |:.||:||::||||::||||||..||||:|....:  .|||||:||||||||:|||.:|.||.|:
Mouse   142 WEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLIQYCHSKGIS 206

  Fly   240 ITAYSPLGSPNRPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIPKSVTKDRIE 304
            :|||||||||:||.||..||.:||:.||||||||.:||..|:|||:.:||..:|||||||..||:
Mouse   207 VTAYSPLGSPDRPSAKPEDPSLLEDPKIKEIAAKHEKTSAQVLIRFHIQRNVVVIPKSVTPSRIQ 271

  Fly   305 SNFQVFDFELTPEEIEIIESFECNGRLVPLLNQYGHPHHPFEKD 348
            .|.|||||:|:.||:..|.||..|.|...|........:|::.:
Mouse   272 ENIQVFDFQLSDEEMATILSFNRNWRACLLPETVNMEEYPYDAE 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_001261716.1	ARA1	38..316	CDD:223729	164/270 (61%)
		Tas	45..>248	CDD:223739	121/202 (60%)
Akr1b8	NP_032038.1	ARA1	1..297	CDD:223729	170/284 (60%)
		Tas	16..289	CDD:223739	165/272 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	352	1.000	Domainoid score	I1003
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H116462
Inparanoid	1	1.050	370	1.000	Inparanoid score	I2108
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	1	1.000	-	-		otm43271
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	1	1.100	-	-	O	PTHR11732
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840