Protein Alignment Akr1B and Akr1b7

DIOPT Version :10

• Sequence 1: NP_729726.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_033861.2
• Gene: Akr1b7 / 11997
• MGIID: 101918
• Length: 316
• Species: Mus musculus
• Alignment Length: 306
• Identity: 189/306 - (61%)
• Similarity: 231/306 - (75%)
• Gaps: 3/306 - (0%)

  Fly    47 EIPVIGLGTFNSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEGVVKREDLFIT 111
            ::|::||||:.|..|||.||||.|||||||||||||||.||:|||:.::.||||..||||||||.
Mouse    12 KMPLVGLGTWKSSPGQVKEAVKAAIDAGYRHIDCAYVYHNENEVGEAIQEKIKENAVKREDLFIV 76

  Fly   112 SKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDGKTLYSPVDYVDT 176
            ||||.||....|||.|.:||||.|||.||||||:|||.|::.|..|.|.|..||.|.|...::|.
Mouse    77 SKLWATFFEKSLVKKAFQNTLSDLKLDYLDLYLVHWPQGFQAGNALLPKDNKGKVLLSKSTFLDA 141

  Fly   177 WKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATI--PPVTNQIECHPYLTQKKLIDFCKSKDIT 239
            |:|||:||::||||::|:||||..||||:|....:  .|||||||.||||||:|||.:|:||.|.
Mouse   142 WEAMEELVDQGLVKALGISNFNHFQIERLLNKPGLKHKPVTNQIESHPYLTQEKLIQYCQSKGIA 206

  Fly   240 ITAYSPLGSPNRPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIPKSVTKDRIE 304
            :|||||||||:||:||..|||::|..||||||||.|||..|:|||:.|||..:|||||||..||:
Mouse   207 VTAYSPLGSPDRPYAKPEDPVVMEIPKIKEIAAKHKKTVAQVLIRFHVQRNVVVIPKSVTPSRIQ 271

  Fly   305 SNFQVFDFELTPEEIEIIESFECNGRLVPLLKDAGTHKYYPFHDEY 350
            .|.|||||:|:.|::..|.||..|.|...|| ||.|.:.||||:||
Mouse   272 ENLQVFDFQLSEEDMAAILSFNRNWRACDLL-DARTEEDYPFHEEY 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_729726.1	AKR_SF	45..350	CDD:444925	187/304 (62%)
Akr1b7	NP_033861.2	AKR_AKR1B1-19	10..316	CDD:381333	187/304 (62%)