Protein Alignment Akr1B and Akr1c20

DIOPT Version :10

• Sequence 1: NP_729726.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_001298061.1
• Gene: Akr1c20 / 116852
• MGIID: 2151104
• Length: 323
• Species: Mus musculus
• Alignment Length: 319
• Identity: 158/319 - (49%)
• Similarity: 219/319 - (68%)
• Gaps: 11/319 - (3%)

  Fly    40 VVCLDGNEIPVIGLGTF---NSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEG 101
            |:..||:.||::|.||.   ..|:.:.|||.|:|||||:||||||.|||||.|||..:.:||.:|
Mouse     8 VLLNDGHFIPILGFGTSAPQEVPRSKATEATKIAIDAGFRHIDCAAVYQNEKEVGLAIRSKIVDG 72

  Fly   102 VVKREDLFITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDGKT 166
            .|||||:|.|||:|.|||||:||:..||.:|..|:|.|:||||||:|:..|.|.:.||.|::||.
Mouse    73 TVKREDIFCTSKVWQTFHRPELVQVCLEQSLKQLQLDYVDLYLIHFPIAMKPGENYFPKDENGKF 137

  Fly   167 LYSPVDYVDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATI--PPVTNQIECHPYLTQKKL 229
            :|..||..|||:||||..:.||.|||||.||||||:|::|....:  .||.||:||||||.|:||
Mouse   138 IYDAVDICDTWEAMEKCKDAGLAKSIGVCNFNRRQLEKILSKPGLKYKPVCNQVECHPYLNQRKL 202

  Fly   230 IDFCKSKDITITAYSPLGS-PNRPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIV 293
            :|||:||||.:.|:|.||| .::.|.....||:|::..:..:|.|..:||..|.:||||||..:|
Mouse   203 LDFCRSKDIVLVAHSALGSNRDKEWVDKSFPVLLDDPVLGSMAKKYNRTPALIALRYQVQRGVVV 267

  Fly   294 IPKSVTKDRIESNFQVFDFELTPEEIEIIESFECNGRLV--PLLKDAGTHKYYPFHDEY 350
            :.||..:.||:.|.|||:|:||..::::::....|.|.:  .:.:|   |..:||.|||
Mouse   268 LAKSFIEKRIKENMQVFEFQLTSVDMKVLDGLNKNIRYIGSSISED---HPDFPFLDEY 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_729726.1	AKR_SF	45..350	CDD:444925	154/312 (49%)
Akr1c20	NP_001298061.1	AKR_AKR1C1-35	6..306	CDD:381334	151/297 (51%)