Protein Alignment Akr1B and Akr1b3

DIOPT Version :9

• Sequence 1: NP_001261716.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_033788.3
• Gene: Akr1b3 / 11677
• MGIID: 1353494
• Length: 316
• Species: Mus musculus
• Alignment Length: 307
• Identity: 182/307 - (59%)
• Similarity: 226/307 - (73%)
• Gaps: 2/307 - (0%)

  Fly    44 DGNEIPVIGLGTFNSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIKEGVVKREDL 108
            :|.::|.:||||:.||.||||||||||||.||||||||.|||||.|||..::.|:||.||||:||
Mouse     9 NGTKMPTLGLGTWKSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQDL 73

  Fly   109 FITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKDGKTLYSPVDY 173
            ||.||||.|||...:||.|.:.|||.|:|.||||||||||.|:|.|.|.||.|..|..:.|..|:
Mouse    74 FIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDASGNVIPSDTDF 138

  Fly   174 VDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATI--PPVTNQIECHPYLTQKKLIDFCKSK 236
            ||||.|||:||:|||||:|||||||..||||:|....:  .|..|||||||||||:|||::|.||
Mouse   139 VDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHSK 203

  Fly   237 DITITAYSPLGSPNRPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRANIVIPKSVTKD 301
            .|.:|||||||||:|||||..||.:||:.:||.||||..||..|:|||:.:||..:|||||||..
Mouse   204 GIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYNKTTAQVLIRFPIQRNLVVIPKSVTPV 268

  Fly   302 RIESNFQVFDFELTPEEIEIIESFECNGRLVPLLNQYGHPHHPFEKD 348
            ||..|.:|||||::.|::..:.|:..|.|:..|::...|..:||..:
Mouse   269 RIAENLKVFDFEVSSEDMATLLSYNRNWRVCALMSCAKHKDYPFHAE 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_001261716.1	ARA1	38..316	CDD:223729	174/273 (64%)
		Tas	45..>248	CDD:223739	133/204 (65%)
Akr1b3	NP_033788.3	ARA1	1..297	CDD:223729	177/287 (62%)
		Tas	8..289	CDD:223739	175/279 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845414
Domainoid	1	1.000	352	1.000	Domainoid score	I1003
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	370	1.000	Inparanoid score	I2108
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	1	1.000	-	-		otm43271
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	1	1.100	-	-	O	PTHR11732
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1770
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.800