Protein Alignment Akr1B and Akr1c14

DIOPT Version :9

• Sequence 1: NP_001261716.1
• Gene: Akr1B / 39304
• FlyBaseID: FBgn0086254
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_598833.1
• Gene: Akr1c14 / 105387
• MGIID: 2145458
• Length: 323
• Species: Mus musculus
• Alignment Length: 320
• Identity: 152/320 - (47%)
• Similarity: 214/320 - (66%)
• Gaps: 7/320 - (2%)

  Fly    37 APKVVCLDGNEIPVIGLGTF---NSPKGQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKI 98
            :|:||..||:.||.:|.||.   ..||.::.:|.|:|||.|:||.|.||:||.|:|||..:.:||
Mouse     5 SPRVVLNDGHFIPALGFGTTVPDKVPKDELIKATKIAIDTGFRHFDSAYLYQIEEEVGQAIRSKI 69

  Fly    99 KEGVVKREDLFITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKEGCDLFPTDKD 163
            ::|.|||||:|.|||||:|||||:||:|.||.||.:.:|.|:|||:||:||..:.|..|||.|:.
Mouse    70 EDGTVKREDIFYTSKLWSTFHRPELVRSCLEKTLKNAQLDYVDLYIIHFPMALQPGDKLFPRDEH 134

  Fly   164 GKTLYSPVDYVDTWKAMEKLVEEGLVKSIGVSNFNRRQIERVLEVATI--PPVTNQIECHPYLTQ 226
            ||.|...||..|||:||||..:.||.|||||||||.||:|.:|....:  .||.||:|||.||.|
Mouse   135 GKLLAEAVDLCDTWEAMEKCKDAGLAKSIGVSNFNFRQLETILNKPGLKYKPVCNQVECHLYLNQ 199

  Fly   227 KKLIDFCKSKDITITAYSPLGSP-NRPWAKAGDPVILEEAKIKEIAAKKKKTPGQILIRYQVQRA 290
            .:::|:||||||.:.:|..|||. ::.|.....||:|::..:..:|.|.|:||..|.||||:||.
Mouse   200 SQMLDYCKSKDIILVSYCTLGSSRDKIWVDQKSPVLLDDPVLCAMANKYKQTPALIAIRYQLQRG 264

  Fly   291 NIVIPKSVTKDRIESNFQVFDFELTPEEIEIIESFECNGRLVPLLNQYGHPHHPFEKDEY 350
            .:|:.:|..:.||:...:||:|:|..|::::::....|.|.........||:||| .|||
Mouse   265 IVVLTRSFKEKRIKEFMKVFEFQLASEDMKVLDGLHRNLRYNTASYFDDHPNHPF-TDEY 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akr1B	NP_001261716.1	ARA1	38..316	CDD:223729	141/283 (50%)
		Tas	45..>248	CDD:223739	111/207 (54%)
Akr1c14	NP_598833.1	AKR_AKR1C1-35	6..308	CDD:381334	144/301 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11732
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.930