DRSC/TRiP Functional Genomics Resources

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Protein Alignment Duba and Otud1

DIOPT Version :10

Sequence 1:NP_648482.3 Gene:Duba / 39302 FlyBaseID:FBgn0036180 Length:659 Species:Drosophila melanogaster
Sequence 2:NP_081991.1 Gene:Otud1 / 71198 MGIID:1918448 Length:454 Species:Mus musculus


Alignment Length:318 Identity:77/318 - (24%)
Similarity:125/318 - (39%) Gaps:63/318 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    55 SPQRRGE---VYDELARTH--------RCSPHKSTRSKRREHHEAHAHLYKRDRLEREKLVHPTA 108
            ||.|||.   :.:||.|..        |.:|.::.|..  ||.:|.|  ..:.|......|.|..
Mouse   123 SPPRRGSSAWLLEELLRPDEPAAPNAVRDAPDRNFRLS--EHRQALA--ASQHRAPAPAPVGPEP 183

  Fly   109 AAGSGAPGVSGSKCNSPPS-------TSTSGSSSPSAVGRNSPEHLGLGCTTVPTAQVQMSTSTA 166
            .||.|: |..|.:..:..|       :..|.:|...|:.|..||     ....|......|:...
Mouse   184 GAGPGS-GPWGEERRAERSSRGWDRASGRSDASGSDALRRQDPE-----AEAHPVPAPARSSGEP 242

  Fly   167 AANLLKTVEETFSGYNSGDEHHQPKERLIP--VEEWQRRDLEFAKCMEQRGYELKPVEEDGACLF 229
            |.|        ..|...|.....|::..:.  :.|.:|:|    |.:.||......:..||.||:
Mouse   243 AQN--------GEGEAVGTSRADPRDEKLALYLAEVERQD----KYLRQRNKYRFHIIPDGNCLY 295

  Fly   230 RSISLQIYGDEEMHDVIRQHTMDYIHENREYFGQFVTEDINSYIQRKRARDAHGNHIEIQAISE- 293
            |::|..:|||:.:|..:|:.|:.||.::.::|...:..|:..:|.......|...:.|:.|:.: 
Mouse   296 RAVSKTVYGDQSLHRELREQTVHYIADHLDHFSPLIEGDVGEFIIAAAQDGAWAGYPELLAMGQM 360

  Fly   294 ------------IYSRTVEVYCYQSNPINIFNSEQSQAGYPPLRLSYQRGSHYNAILD 339
                        :.|.||      |..|:....|.|..  |.:.||:....||:|:.|
Mouse   361 LNVNIHLTTGGRLESPTV------STMIHYLGPEDSLR--PSIWLSWLSNGHYDAVFD 410

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DubaNP_648482.3 OTU_OTUD5-like 215..339 CDD:438589 33/136 (24%)
PTZ00449 <432..>634 CDD:185628
Otud1NP_081991.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 36..64
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 116..257 36/151 (24%)
OTU_OTUD1 262..410 CDD:438584 39/159 (25%)
Cys-loop. /evidence=ECO:0000250|UniProtKB:Q5VV17 287..293 2/5 (40%)
His-loop. /evidence=ECO:0000250|UniProtKB:Q5VV17 342..352 1/9 (11%)
Variable-loop. /evidence=ECO:0000250|UniProtKB:Q5VV17 399..404 0/4 (0%)
Blue background indicates that the domain is not in the aligned region.

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