Protein Alignment Duba and otub-4

DIOPT Version :10

• Sequence 1: NP_648482.3
• Gene: Duba / 39302
• FlyBaseID: FBgn0036180
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: NP_500333.3
• Gene: otub-4 / 177104
• WormBaseID: WBGene00015249
• Length: 436
• Species: Caenorhabditis elegans
• Alignment Length: 497
• Identity: 160/497 - (32%)
• Similarity: 231/497 - (46%)
• Gaps: 138/497 - (27%)

  Fly    94 KRDRLEREKLVHPTAAAGSGAPG----VSGSKCNS------------------PP------STST 130
            ||::..:::.|   :..||.|..    :||..|:|                  ||      |.|:
 Worm     9 KREKDSQQRSV---STIGSSAENSRQQLSGPSCSSSASSSSSAAKRIRSQEDGPPSKRWVLSASS 70

  Fly   131 SGSSSPSAVGRNSPEHLGLGCTTVPTAQVQMSTSTAAANLLKTVEETFSGYNSGDEHHQPKERLI 195
            :.|::.|.:..:||      ....|..:::.:.|.:..|         :.|||.||:.....|..
 Worm    71 TSSTNKSPIPSSSP------VLPPPQPEIEPNRSQSPGN---------ADYNSDDEYEMQNIRDD 120

  Fly   196 PVEEWQRRDLEFAKCMEQRGYELKPVEEDGACLFRSISLQIYGDEEMHDVIRQHTMDYIHENREY 260
            .:|      .||:..:..||..:|.:..||||:||||:.|||||:|||..||:..|||:..||::
 Worm   121 EIE------TEFSNRLAARGLIIKEMVGDGACMFRSIAEQIYGDQEMHGQIRRLCMDYMSNNRDH 179

  Fly   261 FGQFVTEDINSYIQRKRARDAHGNHIEIQAISEIYSRTVEVYCYQSNPINIF------------- 312
            |.:|:||:..:||||||..:.||||:|:|||||:::|.||||.|...|||:.
 Worm   180 FKEFITENFENYIQRKREENVHGNHVELQAISEMFARPVEVYQYSDEPINVLLPRPEPEATALTD 244

  Fly   313 -NSEQSQAG----------YPPLRLSYQRGSHYNAILDPYNATVGVGLGLAGYKPEIQTKE---- 362
             ::..|.|.          .|||||||.|..||||||.|...|:|:||||.|..|....||
 Worm   245 GSASTSNAAPPPSTVPIQQNPPLRLSYHRAVHYNAILAPNIPTIGIGLGLPGMIPGSADKELMST 309

  Fly   363 AVRLSEQLEIEQTMFEDKLKTTDWEATNEAIEEQIARESYLQWCRENTQRSRNS-NTAAGSATSS 426
            |::.||...||:||.:||:..||::.|...||:||.|||.:.:..: .::|:|: :|:||:
 Worm   310 AMKTSELEHIEETMLQDKIDMTDFQRTQADIEDQITRESLISYLND-FEKSKNAPSTSAGA---- 369

  Fly   427 TVTSAEALTDSDASPSKYSACGGTGSSGNPPVALTSGSGGDGAGPAFSLSPKTLNQFSHKLPQEV 491
                        ..||.:        ||.|||   ||||                .:...|..:.
 Worm   370 ------------PGPSNF--------SGEPPV---SGSG----------------LYEEMLAAQS 395

  Fly   492 NELGGYDSDAT-----------DMSSTSSVGHSGGSSSPSTA 522
            .|...|..|..           .||:..|...||  |.|||:
 Worm   396 LEWDAYTDDVAIAEAMLVSQQDYMSNKPSTSSSG--SGPSTS 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Duba	NP_648482.3	OTU_OTUD5-like	215..339	CDD:438589	69/147 (47%)
		PTZ00449	<432..>634	CDD:185628	24/102 (24%)
otub-4	NP_500333.3	OTU_OTUD5-like	134..280	CDD:438589	67/145 (46%)