Protein Alignment Duba and Duba

DIOPT Version :10

• Sequence 1: NP_648482.3
• Gene: Duba / 39302
• FlyBaseID: FBgn0036180
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: XP_061496750.1
• Gene: Duba / 1281343
• VectorBaseID: AGAMI1_014488
• Length: 709
• Species: Anopheles gambiae
• Alignment Length: 746
• Identity: 289/746 - (38%)
• Similarity: 392/746 - (52%)
• Gaps: 145/746 - (19%)

  Fly     1 MTIKPVSAPPSAKRVAGNVDPDNKEAQVVVVEQSVVSQTHNHAH-----NHRNVVI------DGQ 54
            ||||||....|||.......|.|               .|...:     :|||||:      :.|
Mosquito     1 MTIKPVVNQKSAKEETQEGTPQN---------------VHGVGNAGVRTSHRNVVLNQLSSSESQ 50

  Fly    55 SPQRRGEVY-------DELARTHRCSPHKSTRSKRREHHEAHAHLYKRDRLEREKLVHPTAAAGS 112
            :..|...|.       |.:.| ||.||||:....:|:|:      :||:..||||      |.||
Mosquito    51 ALPREKRVLTPHSFDSDSVVR-HRRSPHKNLGRLKRDHY------HKRESREREK------ATGS 102

  Fly   113 GA--------PGVSGSK----CNSPPSTSTSGSSSPSAVGRNSPEHLGLGCTTVPTAQ-VQMSTS 164
            .:        |..||.|    |:|..:::..|..||.:..::.    |.|.:.:.:.| |..|..
Mosquito   103 PSYHHHVVLQPSASGKKQSTACSSTLASAAGGGRSPKSTHQSG----GAGGSLLNSHQAVVGSPG 163

  Fly   165 TAAANLLKTVEETFSGYNSGDEHHQPKERLIPVEEWQRRDLEFAKCMEQRGYELKPVEEDGACLF 229
            .:..:|...:|:..||||||||:...|:..:..:||::||..|||.:.:||:.|..:||||||||
Mosquito   164 ASGVDLNAVLEDVRSGYNSGDEYIDSKDAQLTADEWKKRDEAFAKVLSERGFILHEMEEDGACLF 228

  Fly   230 RSISLQIYGDEEMHDVIRQHTMDYIHENREYFGQFVTEDINSYIQRKRARDAHGNHIEIQAISEI 294
            |:||||||||:|||:.|||.|||||::|||||.|||||||..|::||||...|||||||||:||:
Mosquito   229 RAISLQIYGDQEMHEAIRQQTMDYIYQNREYFAQFVTEDIADYVERKRANHVHGNHIEIQAMSEM 293

  Fly   295 YSRTVEVYCYQSNPINIFNSEQSQAGYPPLRLSYQRGSHYNAILDPYNATVGVGLGLAGYKPE-- 357
            |:|:||:||||:.|.|||||:|...|..|.||||||.||||||::||.|:||||||||||:|:
Mosquito   294 YNRSVELYCYQTEPTNIFNSDQINNGNEPFRLSYQRSSHYNAIVNPYKASVGVGLGLAGYRPDEL 358

  Fly   358 --IQTKEAVRLSEQLEIEQTMFEDKLKTTDWEATNEAIEEQIARESYLQWCRENTQRSRNSNTAA 420
              .|..:|||:||:||||:||.||||||||||||||.||||||||||.|:||| .:......::.
Mosquito   359 DIKQVADAVRMSEELEIEKTMLEDKLKTTDWEATNEEIEEQIARESYAQYCRE-ARLGAGGGSSQ 422

  Fly   421 GSATSSTVTSAE---ALTDSDASPSKY-------SACGGTGSSGNPPVALTSGSGGD-GA----- 469
            ..:||||:||.|   |......|.|.|       ......|:...||:  :||.|.| ||
Mosquito   423 NKSTSSTITSTEMMAACASGSQSASSYLLELRKSPPSASHGNQQQPPI--SSGMGSDRGACSSSS 485

  Fly   470 -GPAFSL-----SPKTLNQFSHKLPQEVNELGGYDSDATDMSSTSSVGHSGGSSSPSTAASQRSG 528
             ..:|.|     ||.:..|..:           |.|.|      ||.|:..||::.||:.|....
Mosquito   486 KNSSFELDCCSSSPSSSQQHYY-----------YGSGA------SSNGNGTGSNNNSTSCSSECN 533

  Fly   529 KGSK---------------SQRRATALRKKRRHETRETTLASKSAEALEAPLRKSPKRDSAPSVA 578
            :..|               .:..:...:|.:.:..|.::.:|.|....|:|..:.....|.||.:
Mosquito   534 RRKKRNINSPFQLNLPNRIEKTNSAETKKCKANGNRTSSTSSNSPRRSESPAEEKSPTPSPPSTS 598

  Fly   579 RADTPEAEQRPSTSKQSSHS-----------PQKNVDSKSPT--EQSYSSFYQELLEASYANEGA 630
            ....|.|  |..|.::||.|           |.....|...|  |...|.|||.|||:||.::|:
Mosquito   599 STMPPPA--RDGTEEESSSSGSGGAGASALFPSSLPPSTGATRDETPMSEFYQSLLESSYTDDGS 661

  Fly   631 ----NESEMLQQAIQMSTRDYME--DQKRKF 655
                :|.||:|:|::.|..|:::  |..:.|
Mosquito   662 FGQLSEREMIQKALEESAMDFVKRGDNSKAF 692

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Duba	NP_648482.3	OTU_OTUD5-like	215..339	CDD:438589	87/123 (71%)
		PTZ00449	<432..>634	CDD:185628	62/255 (24%)
Duba	XP_061496750.1	None