Protein Alignment CG7368 and ZNF131

DIOPT Version :10

• Sequence 1: NP_001036599.1
• Gene: CG7368 / 39301
• FlyBaseID: FBgn0036179
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001284477.1
• Gene: ZNF131 / 7690
• HGNCID: 12915
• Length: 623
• Species: Homo sapiens
• Alignment Length: 520
• Identity: 95/520 - (18%)
• Similarity: 165/520 - (31%)
• Gaps: 201/520 - (38%)

  Fly   173 ILQQQVLQNTSWQTLTPGTTVADYLSHLPA----------NTLPLSLHHFLKYSAETIKKENQQN 227
            ::|.:...|..|:       .|::|..|.|          |:.||..:...|..|:..|.....|
Human    95 MIQGEEEANDVWK-------AAEFLQMLEAIKALEVRNKENSAPLEENTTGKNEAKKRKIAETSN 152

  Fly   228 VVLQVQTGPAIGINTLGTTTISIPQ-QAEQLTLQPQ-QQATLQVQTQAAVT-------------- 276
            |:                 |.|:|. ::|.:.::.: .:.|::|:.:...|
Human   153 VI-----------------TESLPSAESEPVEIEVEIAEGTIEVEDEGIETLEEVASAKQSVKYI 200

  Fly   277 -ATATTATATTAGGSGATSGKKKKRKKRSKDRKTKLRPG-----------------EIRLGTALD 323
             :|.::..:..|..:..||      |.|..|||.:::..                 |::|....|
Human   201 QSTGSSDDSALALLADITS------KYRQGDRKGQIKEDGCPSDPTSKQVEGIEIVELQLSHVKD 259

  Fly   324 GSPLYMCPECHVAYPEPELLEVHLVGHNLE--------KRY------------------------ 356
               |:.|.:|:.::......:.|:..|:.|        |||
Human   260 ---LFHCEKCNRSFKLFYHFKEHMKSHSTESFKCEICNKRYLRESAWKQHLNCYHLEEGGVSKKQ 321

  Fly   357 -------VCDICQASLKRKDHLTRHKQSHNPERP------------------------------- 383
                   ||..|:.......|...|.:.|..|:|
Human   322 RTGKKIHVCQYCEKQFDHFGHFKEHLRKHTGEKPFECPNCHERFARNSTLKCHLTACQTGVGAKK 386

  Fly   384 -----YICTVCLKAFKRKEQLSLHFVIHSGEKRHQCGECGKGFYRKDHLRKHTRS--HIARRVKA 441
                 |.|.||...|...:|...|.|||:|:|.:.|..|...|.:.:.||:|...  :|:.|:..
Human   387 GRKKLYECQVCNSVFNSWDQFKDHLVIHTGDKPNHCTLCDLWFMQGNELRRHLSDAHNISERLVT 451

  Fly   442 E----LNSHVRRENGTSM--------------LQPVVTEATTAALQ-HANQLASAQ------QQL 481
            |    :.:.|:.|..|||              ||..|..|.....| |.:.|..:|      .:|
Human   452 EEVLSVETRVQTEPVTSMTIIEQVGKVHVLPLLQVQVDSAQVTVEQVHPDLLQDSQVHDSHMSEL 516

  Fly   482 QQQQQ-------QQQQQQQQQQQQQQHHIVITQQ---------------QATPQQQQQTSQQQQQ 524
            .:|.|       :.|.::..:...::.|:....|               ..||:...|..::..|
Human   517 PEQVQVSYLEVGRIQTEEGTEVHVEELHVERVNQMPVEVQTELLEADLDHVTPEIMNQEERESSQ 581

  Fly   525  524
            Human   582  581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7368	NP_001036599.1	C2H2 Zn finger	330..350	CDD:275368	3/19 (16%)
		COG5048	356..>412	CDD:227381	21/122 (17%)
		C2H2 Zn finger	358..378	CDD:275368	4/19 (21%)
		C2H2 Zn finger	386..406	CDD:275368	7/19 (37%)
		zf-C2H2	412..434	CDD:395048	6/23 (26%)
		C2H2 Zn finger	414..434	CDD:275368	6/21 (29%)
ZNF131	NP_001284477.1	BTB_POZ_ZBTB35_ZNF131	16..128	CDD:349530	7/39 (18%)
		Nuclear localization signal 1. /evidence=ECO:0000269|PubMed:17306895	137..148		3/10 (30%)
		COG5048	<262..444	CDD:227381	34/181 (19%)
		C2H2 Zn finger	263..283	CDD:275368	3/19 (16%)
		C2H2 Zn finger	290..311	CDD:275368	3/20 (15%)
		Nuclear localization signal 2. /evidence=ECO:0000269|PubMed:17306895	317..328		0/10 (0%)
		C2H2 Zn finger	330..350	CDD:275368	4/19 (21%)
		zf-H2C2_2	342..367	CDD:463886	5/24 (21%)
		C2H2 Zn finger	358..375	CDD:275368	0/16 (0%)
		C2H2 Zn finger	394..414	CDD:275368	7/19 (37%)
		C2H2 Zn finger	422..439	CDD:275370	5/16 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	573..623		2/9 (22%)