DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7368 and znf513a

DIOPT Version :9

Sequence 1:	NP_001036599.1	Gene:	CG7368 / 39301	FlyBaseID:	FBgn0036179	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_001296396.1	Gene:	znf513a / 568216	ZFINID:	ZDB-GENE-030131-9895	Length:	548	Species:	Danio rerio

Alignment Length:	292	Identity:	75/292 - (25%)
Similarity:	108/292 - (36%)	Gaps:	66/292 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   186 TLTPGTTVADYLSHLPANTLPLS---LHH--FLKYSAETIKKENQQNVVLQVQTGPAIGI--NTL 243
            |:.||.:|          |.|:|   |:|  ..:...|.:....:....::..|.|.:|.  |.|
Zfish   255 TIGPGQSV----------TQPVSGNGLNHSTAAQKEKEAVPAPTEVAGAVRSVTRPHMGRDGNYL 309

  Fly   244 GT-TTISIPQQAEQLTLQPQQQATLQVQTQAAVTATATTATATTAG-------GSGATSGKKKKR 300
            .| ..:.:.||.....||..|.|:    ..||:.......|....|       ||.|....|...
Zfish   310 QTFDGLRLAQQTSTGVLQSGQAAS----QPAALPPMFFPFTCRLCGMALDDEDGSSAQICAKCTL 370

  Fly   301 KKRSKDRKTKLRPGEIRLGTALDGSPLYMCPECHVAYPEPELLEVHLVGHNLEKRYVCDICQASL 365
            :..:||  |...|.|       .|..:|.|..|......|..|..|:..|:.||.|.|..|..:.
Zfish   371 EMLTKD--THGCPAE-------RGDKVYTCAACPFLTHYPNHLARHMKTHSGEKPYKCPQCDYAS 426

  Fly   366 KRKDHLTRHKQSHNPERPYICTVC------LKAFKRKEQ----------------------LSLH 402
            ...|:|.||.:.|..|:||.|.:|      |...||.::                      |..|
Zfish   427 AHFDNLKRHHRVHTGEKPYKCHLCDYACGNLANLKRHQRVHSGAKPFQCAICNYSCNQSMNLKRH 491

  Fly   403 FVIHSGEKRHQCGECGKGFYRKDHLRKHTRSH 434
            .:.|:|||.|:|.|||......|:.::|.:.|
Zfish   492 MLRHTGEKPHKCQECGYTTGHWDNYKRHQKKH 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7368	NP_001036599.1	C2H2 Zn finger	330..350	CDD:275368	5/19 (26%)
		COG5048	356..>412	CDD:227381	22/83 (27%)
		C2H2 Zn finger	358..378	CDD:275368	6/19 (32%)
		zf-H2C2_2	370..395	CDD:290200	10/30 (33%)
		C2H2 Zn finger	386..406	CDD:275368	7/47 (15%)
		zf-H2C2_2	399..423	CDD:290200	11/23 (48%)
		zf-C2H2	412..434	CDD:278523	7/21 (33%)
		C2H2 Zn finger	414..434	CDD:275368	6/19 (32%)
znf513a	NP_001296396.1	C2H2 Zn finger	177..197	CDD:275368
		zf-H2C2_2	189..214	CDD:290200
		COG5048	201..>503	CDD:227381	68/270 (25%)
		C2H2 Zn finger	205..225	CDD:275368
		zf-H2C2_2	217..242	CDD:290200
		C2H2 Zn finger	233..253	CDD:275368
		C2H2 Zn finger	391..411	CDD:275368	5/19 (26%)
		zf-H2C2_2	403..428	CDD:290200	8/24 (33%)
		C2H2 Zn finger	419..439	CDD:275368	6/19 (32%)
		zf-H2C2_2	431..454	CDD:290200	9/22 (41%)
		C2H2 Zn finger	447..467	CDD:275368	5/19 (26%)
		zf-H2C2_2	459..484	CDD:290200	2/24 (8%)
		C2H2 Zn finger	475..495	CDD:275368	2/19 (11%)
		zf-H2C2_2	487..510	CDD:290200	11/22 (50%)
		C2H2 Zn finger	503..523	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24403
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100