DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG7368 and ZFP64

DIOPT Version :9

Sequence 1:NP_001036599.1 Gene:CG7368 / 39301 FlyBaseID:FBgn0036179 Length:530 Species:Drosophila melanogaster
Sequence 2:NP_060667.2 Gene:ZFP64 / 55734 HGNCID:15940 Length:681 Species:Homo sapiens


Alignment Length:377 Identity:79/377 - (20%)
Similarity:131/377 - (34%) Gaps:102/377 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   164 ELTQD--LCNAILQQQ-------VLQNTSWQTLTPGTTVA--DYLSHLPANTLPLSLHHFLKYSA 217
            |||.|  :| .|.:||       |....|...|| ||:.|  ..:..:...|:|.:.   .:.:.
Human    25 ELTPDIHIC-GICKQQFNNLDAFVAHKQSGCQLT-GTSAAAPSTVQFVSEETVPATQ---TQTTT 84

  Fly   218 ETIKKENQQNVVLQVQTGPAIGINTLGTTTISIPQQAEQLTLQPQQQATLQVQTQAAVTATATTA 282
            .||..|.|                   |.|:|.|    :...:...|..|..::....|||..:.
Human    85 RTITSETQ-------------------TITVSAP----EFVFEHGYQTYLPTESNENQTATVISL 126

  Fly   283 TATTAGGSGATSGKKKKRKKRSKDRKTKLRPGEIRLGTALDGSPL-------------------- 327
            .|                  :|:.:|....|.:.||.....|...                    
Human   127 PA------------------KSRTKKPTTPPAQKRLNCCYPGCQFKTAYGMKDMERHLKIHTGDK 173

  Fly   328 -YMCPECHVAYPEPELLEVHLVGHNLEKRYVCDICQASLKRKDHLTRHKQSHNPERPYICTVCLK 391
             :.|..|...:...:.|:.|:..|...|.|.|..|..:......|.:|.:.|:.|||:.|.:|..
Human   174 PHKCEVCGKCFSRKDKLKTHMRCHTGVKPYKCKTCDYAAADSSSLNKHLRIHSDERPFKCQICPY 238

  Fly   392 AFKRKEQLSLHFVIHSGEKRHQCGECGKGFYRKDHLRKHTRSHIARR------------VKAELN 444
            |.:...||::|...|:|:...||..|...|.....|::|.|.|...:            :|..|.
Human   239 ASRNSSQLTVHLRSHTGDAPFQCWLCSAKFKISSDLKRHMRVHSGEKPFKCEFCNVRCTMKGNLK 303

  Fly   445 SHVR-RENGTSMLQPVVTEATTAALQHANQLASAQQQLQQQQQQQQQQQQQQ 495
            ||:| :.:|.:...|           |.:.|..::..|::..:..|.:..::
Human   304 SHIRIKHSGNNFKCP-----------HCDFLGDSKATLRKHSRVHQSEHPEK 344

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7368NP_001036599.1 C2H2 Zn finger 330..350 CDD:275368 4/19 (21%)
COG5048 356..>412 CDD:227381 17/55 (31%)
C2H2 Zn finger 358..378 CDD:275368 4/19 (21%)
zf-H2C2_2 370..395 CDD:290200 9/24 (38%)
C2H2 Zn finger 386..406 CDD:275368 6/19 (32%)
zf-H2C2_2 399..423 CDD:290200 8/23 (35%)
zf-C2H2 412..434 CDD:278523 7/21 (33%)
C2H2 Zn finger 414..434 CDD:275368 6/19 (32%)
ZFP64NP_060667.2 COG5048 <151..450 CDD:227381 42/205 (20%)
zf-H2C2_2 161..186 CDD:290200 2/24 (8%)
C2H2 Zn finger 177..197 CDD:275368 4/19 (21%)
zf-H2C2_2 190..211 CDD:290200 7/20 (35%)
C2H2 Zn finger 205..225 CDD:275368 4/19 (21%)
zf-H2C2_2 217..239 CDD:290200 8/21 (38%)
C2H2 Zn finger 233..253 CDD:275368 6/19 (32%)
C2H2 Zn finger 261..281 CDD:275368 6/19 (32%)
zf-H2C2_2 273..297 CDD:290200 4/23 (17%)
C2H2 Zn finger 289..308 CDD:275368 4/18 (22%)
C2H2 Zn finger 373..391 CDD:275368
zf-C2H2_6 425..450 CDD:290623
C2H2 Zn finger 427..447 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24403
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

Return to query results.
Submit another query.