DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7368 and l(3)neo38

DIOPT Version :9

Sequence 1:	NP_001036599.1	Gene:	CG7368 / 39301	FlyBaseID:	FBgn0036179	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_001262485.1	Gene:	l(3)neo38 / 41423	FlyBaseID:	FBgn0265276	Length:	455	Species:	Drosophila melanogaster

Alignment Length:	490	Identity:	186/490 - (37%)
Similarity:	252/490 - (51%)	Gaps:	100/490 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNFTPFGNTFPGNIPGLPQFTTSTAPLVSTVTAAVTDVTVTGTNNPQQQQQQDAAGSSNRYQQQQ 65
            |||:.||..|.|......:|...|.....|..||..:......          |||:.|..|:.|
  Fly     2 MNFSAFGGPFSGIHQFAAKFDAQTPGAFGTPPAAAANAAAAAA----------AAGTDNHVQRYQ 56

  Fly    66 QQVTHFGQATMTAGQGSSGNKFRGGQDDAI-----QGDKYNGHLVASSQQQQQQQQQQQTQYATV 125
            ....||.|.....   |:.|..:.||:.:|     |||                          :
  Fly    57 TNGNHFNQNVPNV---SAANNMQYGQNISIPYSQPQGD--------------------------L 92

  Fly   126 AYASATATSAATDALQAGTSGQQQQQQQMQQQQVTAPQELTQDLCNAILQQQVLQNT--SWQTLT 188
            .:.:|.|.        |...|:...:.:..:::|              |.||:|||.  |||||.
  Fly    93 NFLNAAAA--------ADHKGKIHPKIERDREEV--------------LNQQILQNVNQSWQTLA 135

  Fly   189 PGTTVADYLSHLPANTLPLSLHHFLKYSAETIKKENQQNVVLQ-----------VQTGPA----- 237
            ......||.|||.:.|||:|:.|||||| ||||||:..:|:..           |...|:
  Fly   136 NTANTVDYSSHLLSATLPISIQHFLKYS-ETIKKESTGDVLKNGTNLASLALGGVALTPSNNGAN 199

  Fly   238 -------IGINTLGTTTISIPQQAEQLT------LQPQQQATLQVQTQAAVTATATTATATTAGG 289
                   :|::..|..|.........||      :......|:......||:::.:..|...:||
  Fly   200 GGHHNGLVGMDHGGHMTNMTDANGAALTNGASNGVNGNANGTVTNGGAGAVSSSGSVGTTNASGG 264

  Fly   290 SGATSGKKKKRKKRSKDRKTKLRPGEIRLGTALDGSPLYMCPECHVAYPEPELLEVHLVGHNLEK 354
            :|..||||.|:||..|::|.:.:|||||...|||||.||.||||.:|||:..|:|.|::.|.:|:
  Fly   265 TGTASGKKTKKKKPPKEKKPRPKPGEIRETKALDGSTLYCCPECQMAYPDRSLIEQHVISHAVER 329

  Fly   355 RYVCDICQASLKRKDHLTRHKQSHNPERPYICTVCLKAFKRKEQLSLHFVIHSGEKRHQCGECGK 419
            |:|||||.|:|||||||||||.||.|:||::|.:|:|:|||||||:||.|||||||:|.|.||||
  Fly   330 RFVCDICNAALKRKDHLTRHKLSHIPDRPHVCNICMKSFKRKEQLTLHIVIHSGEKKHVCIECGK 394

  Fly   420 GFYRKDHLRKHTRSHIARRVKAELNSHVRRENGTS 454
            |||||||||||||||||||||:|:::  :..||::
  Fly   395 GFYRKDHLRKHTRSHIARRVKSEVSA--QNVNGSA 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7368	NP_001036599.1	C2H2 Zn finger	330..350	CDD:275368	10/19 (53%)
		COG5048	356..>412	CDD:227381	41/55 (75%)
		C2H2 Zn finger	358..378	CDD:275368	16/19 (84%)
		zf-H2C2_2	370..395	CDD:290200	15/24 (63%)
		C2H2 Zn finger	386..406	CDD:275368	13/19 (68%)
		zf-H2C2_2	399..423	CDD:290200	18/23 (78%)
		zf-C2H2	412..434	CDD:278523	19/21 (90%)
		C2H2 Zn finger	414..434	CDD:275368	18/19 (95%)
l(3)neo38	NP_001262485.1	C2H2 Zn finger	305..325	CDD:275368	10/19 (53%)
		zf-C2H2_8	306..391	CDD:292531	55/84 (65%)
		C2H2 Zn finger	333..353	CDD:275368	16/19 (84%)
		zf-H2C2_2	345..370	CDD:290200	15/24 (63%)
		C2H2 Zn finger	361..381	CDD:275368	13/19 (68%)
		zf-H2C2_2	374..398	CDD:290200	18/23 (78%)
		C2H2 Zn finger	389..409	CDD:275368	18/19 (95%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BP5H
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	44	1.000	Inparanoid score	I2683
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D427352at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.870