DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7368 and znf131

DIOPT Version :9

Sequence 1:	NP_001036599.1	Gene:	CG7368 / 39301	FlyBaseID:	FBgn0036179	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_956799.2	Gene:	znf131 / 393477	ZFINID:	ZDB-GENE-040426-1563	Length:	558	Species:	Danio rerio

Alignment Length:	275	Identity:	54/275 - (19%)
Similarity:	90/275 - (32%)	Gaps:	83/275 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   328 YMCPECHVAYPEPELLEVHLVGHNLE----------KRYVCDICQASLKRKDHLTRHKQSHNPER 382
            ::|..|..||.....|:.||..::.:          |.:||:.|:.......|...|.:.|..|:
Zfish   287 FVCRHCGKAYAREGALKQHLNNYHFDAEEQSRRQKKKVHVCEYCEKQFDHFGHFKEHLRKHTGEK 351

  Fly   383 P------------------------------------YICTVCLKAFKRKEQLSLHFVIHSGEKR 411
            |                                    |.|.||...|...||...|.|.|:|||.
Zfish   352 PFECPECHERFARNSTLKCHMSACQNGSGAKKGRKKLYECQVCSSVFNSWEQFKDHLVTHTGEKP 416

  Fly   412 HQCGECGKGFYRKDHLRKHTRSHIARRVK---AE---------------------LNSHVRRENG 452
            :.|..|...|.....|..|.:.|.:.:.|   ||                     |...:|.|:.
Zfish   417 NHCTLCDLWFTSPRDLHTHLQEHHSLQEKVIVAEDILISDPANVLSMEEGEERVILEDGIRVEHV 481

  Fly   453 TSMLQPVVTEATTAALQHANQLASAQQQ--------LQQQQQQQQQQQQQQQQQQQHHIVITQQQ 509
            |.....||....|..::...|:..:|.:        ||...::.::|....|.:::     |..:
Zfish   482 TVEPVDVVAVEETLVVEEETQIQPSQPEGGVAETVVLQVDSEKLKEQVMGIQVERE-----TVAE 541

  Fly   510 ATPQQQQQTSQQQQQ 524
            ....:|:..|.::.:
Zfish   542 PAEAKQEPASCEKTE 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7368	NP_001036599.1	C2H2 Zn finger	330..350	CDD:275368	7/19 (37%)
		COG5048	356..>412	CDD:227381	21/91 (23%)
		C2H2 Zn finger	358..378	CDD:275368	4/19 (21%)
		zf-H2C2_2	370..395	CDD:290200	10/60 (17%)
		C2H2 Zn finger	386..406	CDD:275368	8/19 (42%)
		zf-H2C2_2	399..423	CDD:290200	9/23 (39%)
		zf-C2H2	412..434	CDD:278523	5/21 (24%)
		C2H2 Zn finger	414..434	CDD:275368	5/19 (26%)
znf131	NP_956799.2	BTB	24..120	CDD:306997
		zf-C2H2	257..279	CDD:306579
		C2H2 Zn finger	259..279	CDD:275368
		C2H2 Zn finger	289..347	CDD:275368	13/57 (23%)
		COG5048	<310..441	CDD:227381	28/130 (22%)
		C2H2 Zn finger	327..344	CDD:275368	3/16 (19%)
		zf-H2C2_2	339..364	CDD:316026	5/24 (21%)
		C2H2 Zn finger	355..372	CDD:275368	0/16 (0%)
		C2H2 Zn finger	419..439	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24403
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100