DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7368 and CG15073

DIOPT Version :9

Sequence 1:	NP_001036599.1	Gene:	CG7368 / 39301	FlyBaseID:	FBgn0036179	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_611362.2	Gene:	CG15073 / 37155	FlyBaseID:	FBgn0034379	Length:	580	Species:	Drosophila melanogaster

Alignment Length:	432	Identity:	93/432 - (21%)
Similarity:	145/432 - (33%)	Gaps:	109/432 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 RGGQDDAIQGDKYNGHLVASSQQQQQQQQQQQTQYATVAYASATATSAATDALQAGTSGQQQQQQ 152
            :.|||   ||...:|.  .|.||:::|.:.|:.........|.|.....|:.:          .|
  Fly    82 KSGQD---QGKVEHGE--DSEQQEEEQDEDQELGLPGSEGGSFTNEQFLTEVI----------AQ 131

  Fly   153 QMQQQQVTAPQELTQDLCNAILQQQVLQNTSWQTLTPGTTVADYLSHLPA-------NTLPLSLH 210
            |.||.....|:|            |.::..:.....|.|:..     ||.       :|.....|
  Fly   132 QEQQTDSNPPKE------------QFIKEDNATVNDPETSAT-----LPTEQRRETRSTAKSKAH 179

  Fly   211 HFLKYSAETIKKENQQNVVLQVQTGPAIGINTLGTTTISIPQQAEQLTLQPQQQATLQVQTQAAV 275
            |.|..|....|..:..|.....:| |.....|        ||::::.....|....:..:..|.:
  Fly   180 HSLPPSTPPEKSNSVANKSKAKRT-PCKAEGT--------PQKSKRYADYKQCMLDIDAKISAHM 235

  Fly   276 TATATTA----------------TATTAGGSGATSGKKKKRK---------------------KR 303
            ..|....                .....|.:...:.|..||.                     ||
  Fly   236 RLTCDVCHEGQETFLLLCKHMLQEHHRKGYAICCNKKFYKRSFLTDHIDRHADPEKFKCTQCDKR 300

  Fly   304 SKDRKTKLRPGEIRLGTALDGSPLYMCPECHVAYPEPELLEVHLVGHNLEKRYVCDICQASLKRK 368
            ..|::. ||..|: |....:....:||.:|...|.:..||:.|.|.|. |:..|||:|:.....:
  Fly   301 FADKQC-LRNHEL-LKHHPEEEKTFMCEQCPKRYTKQYLLDQHRVIHK-ERNVVCDLCERRFPNQ 362

  Fly   369 DHLTRHKQSHNPERPYICTVCLKAFKRKEQLSLHFVIHSG--EKRHQCGECGKGFYRKDHLRKHT 431
            ..|..|.:..:.....:|.:|.:..:.:.....|.:.|:|  |.:.||..||..     |..||:
  Fly   363 SLLCTHVKMAHGNYGTMCDICAQVIRGRAAFQRHQLEHAGVTEPKVQCDICGSW-----HKNKHS 422

  Fly   432 RSHIARRVKAELNSHVRRENGTSM---LQPVVTEATTAALQH 470
                       |..||||.|||:.   |...|:...:|.|.|
  Fly   423 -----------LKKHVRRHNGTAATCDLCGKVSPNRSAMLSH 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7368	NP_001036599.1	C2H2 Zn finger	330..350	CDD:275368	7/19 (37%)
		COG5048	356..>412	CDD:227381	12/57 (21%)
		C2H2 Zn finger	358..378	CDD:275368	5/19 (26%)
		zf-H2C2_2	370..395	CDD:290200	4/24 (17%)
		C2H2 Zn finger	386..406	CDD:275368	3/19 (16%)
		zf-H2C2_2	399..423	CDD:290200	8/25 (32%)
		zf-C2H2	412..434	CDD:278523	7/21 (33%)
		C2H2 Zn finger	414..434	CDD:275368	6/19 (32%)
CG15073	NP_611362.2	zf-AD	2..78	CDD:285071
		C2H2 Zn finger	269..286	CDD:275368	3/16 (19%)
		C2H2 Zn finger	294..316	CDD:275368	7/23 (30%)
		C2H2 Zn finger	325..345	CDD:275368	7/19 (37%)
		C2H2 Zn finger	352..370	CDD:275368	5/17 (29%)
		C2H2 Zn finger	410..430	CDD:275368	10/35 (29%)
		C2H2 Zn finger	437..458	CDD:275368	5/17 (29%)
		C2H2 Zn finger	466..486	CDD:275368
		C2H2 Zn finger	494..512	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24403
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100