DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7368 and Zfp462

DIOPT Version :9

Sequence 1:NP_001036599.1 Gene:CG7368 / 39301 FlyBaseID:FBgn0036179 Length:530 Species:Drosophila melanogaster
Sequence 2:XP_038966959.1 Gene:Zfp462 / 362522 RGDID:1562123 Length:2565 Species:Rattus norvegicus


Alignment Length:486 Identity:78/486 - (16%)
Similarity:161/486 - (33%) Gaps:128/486 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    56 GSSNRYQQQQQQVTHFGQATMTAGQGSSGNKFRGGQDDAIQGDKYNGHLVASSQQQQQQQQQQQT 120
            ||..|:|....|..|......:..:.:|...        |..:::...   :.:|::::|...:.
  Rat  1880 GSGPRFQNSTFQCKHCDSKLQSTAELTSHLN--------IHNEEFQKR---AKRQERRKQLLSKQ 1933

  Fly   121 QYATVAYASATATSAATDALQAGTSGQQQQQQQMQQQQVTAPQELTQDLCNAILQQQVLQNTSWQ 185
            :||..|:|         |..|....|..::..::::::|...:      |...::          
  Rat  1934 KYADGAFA---------DFKQERPFGHLEEAPKIKERKVVGYK------CKFCVE---------- 1973

  Fly   186 TLTPGTTVADYLSHLPANTLPLSLHHFLKYSAETIKKENQQNVVLQVQTGPAIGINTLGTTTISI 250
                                   :|..|:.....::|..|...|      ||:        :.::
  Rat  1974 -----------------------VHPTLRAICNHLRKHVQYGSV------PAV--------SAAV 2001

  Fly   251 PQQAEQLTLQPQQQATLQVQTQAAVTATATTATATTAGGSGATSGKKKKRKKRSKDRKTKLRPGE 315
            .|:||       ..:.|.:....|....:.|......||.....|.          .:.:.|||.
  Rat  2002 KQEAE-------DPSHLFLDGFEAARDASGTLVGRVDGGHCLLDGM----------LEDETRPGG 2049

  Fly   316 IRLGTALDGSPLYMCPECHVAYPEPELLEVHLVGH------NLEKRYVCDICQASLKRKDHLTRH 374
                        |.|.:|.......:.|..|...|      ..|.:|.|..|......:.:|.||
  Rat  2050 ------------YHCSQCDRVLMSMQGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRH 2102

  Fly   375 KQSHN-PERPYICTVCLKAFKRKEQLSLHFV-IHSGEKRHQCGECGKGFYRKDHLRKHTRSHIAR 437
            .|:|: ..:|:.|.:|........:|..|.: .|:||..::|..|.........|::|:      
  Rat  2103 MQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHS------ 2161

  Fly   438 RVKAELNSHVRRENGTSMLQPVVTEATTAALQHANQLASAQQQLQQQQQQQQQQQQQQQQQQQHH 502
                 |..|.:   ..::.:|.:....::...|::|.|:..::::........:....|||..|:
  Rat  2162 -----LKVHGK---ALTLPRPRIVSLLSSHAHHSSQKATPAEEVEDSNDSSYSEPPDVQQQLNHY 2218

  Fly   503 ----IVITQQQATPQQQQQTSQQQQQQQQMI 529
                :.....:.:|.....|:...:|:.:.:
  Rat  2219 QSAALARNNSRVSPVPPSGTAAGTEQKAEAV 2249

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7368NP_001036599.1 C2H2 Zn finger 330..350 CDD:275368 4/19 (21%)
COG5048 356..>412 CDD:227381 16/57 (28%)
C2H2 Zn finger 358..378 CDD:275368 6/19 (32%)
zf-H2C2_2 370..395 CDD:290200 8/25 (32%)
C2H2 Zn finger 386..406 CDD:275368 4/20 (20%)
zf-H2C2_2 399..423 CDD:290200 7/24 (29%)
zf-C2H2 412..434 CDD:278523 4/21 (19%)
C2H2 Zn finger 414..434 CDD:275368 4/19 (21%)
Zfp462XP_038966959.1 C2H2 Zn finger 2052..2072 CDD:275368 4/19 (21%)
zf-H2C2_5 2084..2108 CDD:404746 8/23 (35%)
C2H2 Zn finger 2086..2106 CDD:275368 6/19 (32%)
C2H2 Zn finger 2115..2136 CDD:275368 4/20 (20%)
C2H2 Zn finger 2144..2165 CDD:275368 5/31 (16%)
C2H2 Zn finger 2315..2335 CDD:275368
C2H2 Zn finger 2361..2381 CDD:275368
C2H2 Zn finger 2389..2410 CDD:275368
C2H2 Zn finger 2475..2495 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24403
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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