DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7368 and Zfp91

DIOPT Version :9

Sequence 1:	NP_001036599.1	Gene:	CG7368 / 39301	FlyBaseID:	FBgn0036179	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_001162591.1	Gene:	Zfp91 / 246282	RGDID:	628736	Length:	568	Species:	Rattus norvegicus

Alignment Length:	447	Identity:	89/447 - (19%)
Similarity:	154/447 - (34%)	Gaps:	121/447 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 QQQQQQQQQQQTQYATVAYASATATSAATDALQAGTSGQQQQQQQMQQQQVTAPQE----LTQDL 169
            :.::.:..:||.|..    ..|.|..||:|.|::|.:...:..:....:.:...::    .....
  Rat     4 ETEEPRSPEQQDQEG----GPAAAADAASDELRSGVAAAAKPAETASSRVLRGGRDRGRTAAAAA 64

  Fly   170 CNAILQQQVLQNTSWQTLTPGTTVADYLSHLPANTLPLS---------LHHFLKYSAETIKKENQ 225
            ..|:.:::..:....:..:|.....|...|.||...|.|         |....|.:.:...||.:
  Rat    65 AAAVSRRRKAEYPRRRRSSPSNRPPDGHGHQPAAAKPPSPAQGKKSPRLQCIEKITTDKDPKEEK 129

  Fly   226 QNVVLQVQ------TGPAIGINTLGTTTISIPQQAEQLTLQPQQQATLQV--------------- 269
            ::..:..|      |.|:....:...|:||..:.:|.......:..:||:
  Rat   130 EDDSVLPQEVSITATRPSRSWRSSSRTSISRLRDSENTRSSRSKTGSLQLVCKTEPITDQLDYDV 194

  Fly   270 ----QTQAAVTAT-----------------------------ATTATATTAGGSGATSGKKKKR- 300
                |:.:.:::.                             ....|......||....:|:|:
  Rat   195 PEEHQSPSGISSDEEEEEEEMLISEEEIPFKDDPRDETYKPHLERETPKPRRKSGKVKEEKEKKE 259

  Fly   301 -----------------------KKRSKDRKTKLRPGEIRLGTALDGSPL-YMCPE---CHVAYP 338
                                   :||.:.||....|   ||.......|: |:..|   |.....
  Rat   260 IKVEVEVEVKEEENEIREDEEPPRKRGRRRKDDKSP---RLPKRRKKPPIQYVRCEMEGCGTVLA 321

  Fly   339 EPELLEVHL-VGHNLEKRYVC--DICQASLKRKDHLTRHKQSHNPERPYICTVCLKAFKRKEQLS 400
            .|..|:.|: ..|.|:|:|||  ..|....:.:..|.||.:.|..:|.|||..|.:|||....|:
  Rat   322 HPRYLQHHIKYQHLLKKKYVCPHPSCGRLFRLQKQLLRHAKHHTDQRDYICEYCARAFKSSHNLA 386

  Fly   401 LHFVIHSGEKRHQCGECGKGFYRKDHLRKHTRSHIARRVKAELNSHVRRENGTSMLQ 457
            :|.:||:|||..||..||                ...|.||.||.|:::.:..|..|
  Rat   387 VHRMIHTGEKPLQCEICG----------------FTCRQKASLNWHMKKHDADSFYQ 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7368	NP_001036599.1	C2H2 Zn finger	330..350	CDD:275368	5/23 (22%)
		COG5048	356..>412	CDD:227381	23/57 (40%)
		C2H2 Zn finger	358..378	CDD:275368	5/21 (24%)
		zf-H2C2_2	370..395	CDD:290200	11/24 (46%)
		C2H2 Zn finger	386..406	CDD:275368	7/19 (37%)
		zf-H2C2_2	399..423	CDD:290200	11/23 (48%)
		zf-C2H2	412..434	CDD:278523	4/21 (19%)
		C2H2 Zn finger	414..434	CDD:275368	3/19 (16%)
Zfp91	NP_001162591.1	zf-C2H2_8	311..388	CDD:292531	25/76 (33%)
		C2H2 Zn finger	345..364	CDD:275368	4/18 (22%)
		C2H2 Zn finger	372..392	CDD:275368	7/19 (37%)
		zf-H2C2_2	384..409	CDD:290200	11/40 (28%)
		C2H2 Zn finger	400..420	CDD:275368	9/35 (26%)
		C2H2 Zn finger	430..446	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24403
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100