DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7368 and ZNF513

DIOPT Version :9

Sequence 1:	NP_001036599.1	Gene:	CG7368 / 39301	FlyBaseID:	FBgn0036179	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_653232.3	Gene:	ZNF513 / 130557	HGNCID:	26498	Length:	541	Species:	Homo sapiens

Alignment Length:	146	Identity:	44/146 - (30%)
Similarity:	61/146 - (41%)	Gaps:	24/146 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   310 KLRPGE-IRLGTAL-------------DGSPL------YMCPECHVAYPEPELLEVHLVGHNLEK 354
            :|..|| .|||.|:             .|.|.      :.|..|..|...|..|..|:..|:.||
Human   322 ELEEGEGSRLGAAMCGRCMRGEAGGGASGGPQGPSDKGFACSLCPFATHYPNHLARHMKTHSGEK 386

  Fly   355 RYVCDICQASLKRKDHLTRHKQSHNPERPYICTVCLKAFKRKEQLSLHFVIHSGEKRHQCG---- 415
            .:.|..|..:....|:|.||::.|..|:||.|.:|..|......|..|..||||:|..:|.
Human   387 PFRCARCPYASAHLDNLKRHQRVHTGEKPYKCPLCPYACGNLANLKRHGRIHSGDKPFRCSLCNY 451

  Fly   416 ECGKGFYRKDHLRKHT 431
            .|.:....|.|:.:||
Human   452 SCNQSMNLKRHMLRHT 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7368	NP_001036599.1	C2H2 Zn finger	330..350	CDD:275368	6/19 (32%)
		COG5048	356..>412	CDD:227381	20/55 (36%)
		C2H2 Zn finger	358..378	CDD:275368	6/19 (32%)
		zf-H2C2_2	370..395	CDD:290200	10/24 (42%)
		C2H2 Zn finger	386..406	CDD:275368	5/19 (26%)
		zf-H2C2_2	399..423	CDD:290200	9/27 (33%)
		zf-C2H2	412..434	CDD:278523	6/24 (25%)
		C2H2 Zn finger	414..434	CDD:275368	6/22 (27%)
ZNF513	NP_653232.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..118
		C2H2 Zn finger	152..172	CDD:275368
		COG5048	176..>228	CDD:227381
		C2H2 Zn finger	180..200	CDD:275368
		zf-H2C2_2	192..217	CDD:316026
		C2H2 Zn finger	208..228	CDD:275368
		C2H2 Zn finger	362..382	CDD:275368	6/19 (32%)
		COG5048	<372..>450	CDD:227381	27/77 (35%)
		C2H2 Zn finger	390..410	CDD:275368	6/19 (32%)
		COG5048	414..>487	CDD:227381	18/54 (33%)
		C2H2 Zn finger	418..438	CDD:275368	5/19 (26%)
		C2H2 Zn finger	446..466	CDD:275368	4/19 (21%)
		C2H2 Zn finger	474..493	CDD:275368
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	492..541
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24403
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100