Protein Alignment rt and PMT4

DIOPT Version :10

• Sequence 1: NP_524025.2
• Gene: rt / 39297
• FlyBaseID: FBgn0003292
• Length: 886
• Species: Drosophila melanogaster
• Sequence 2: NP_012677.1
• Gene: PMT4 / 853608
• SGDID: S000003904
• Length: 762
• Species: Saccharomyces cerevisiae
• Alignment Length: 728
• Identity: 226/728 - (31%)
• Similarity: 352/728 - (48%)
• Gaps: 69/728 - (9%)

  Fly   182 LLAFGTRFYKLATPPHIVFDELHYGKYISMYMRNIFFFDQHPPLGKQLIAGLVSLAGYDGNYTFT 246
            ||||..||||:..|..:||||:|:||:.|.|:...:|||.|||..|.:||.:..|.||||::.|.
Yeast    61 LLAFAARFYKIWYPKEVVFDEVHFGKFASYYLERSYFFDVHPPFAKMMIAFIGWLCGYDGSFKFD 125

  Fly   247 RIGEPYSPE-MPIFWFRFLPAMCGSLLAPAVYNLLLEAKLSRWSSALGGLLVVLDNSLLTQSRFV 310
            .||..|... .|...:|...|:.|:|..|.::|.|.|......:.|...|||.:|.:.:|::|.:
Yeast   126 EIGYSYETHPAPYIAYRSFNAILGTLTVPIMFNTLKELNFRAITCAFASLLVAIDTAHVTETRLI 190

  Fly   311 LMESMLLLATTVGIACLLRFQRSRLG---SLEWFFTGTAAAVCLGAAGTVKYVG---FLALGLAF 369
            |::::|:::....:.|.:||.:.:|.   :..|:....|..:.|....:.||||   :.|:|.|.
Yeast   191 LLDAILIISIAATMYCYVRFYKCQLRQPFTWSWYIWLHATGLSLSFVISTKYVGVMTYSAIGFAA 255

  Fly   370 YLLCRHLWQLL-YDAGLTDRQLWMHAISRLLIFVGIPLAVYLGVFYIHFKTLHRAGPHDSIMTSA 433
            .:   :||||| ..|||:.||...|...||...|.||..:||..|::||..|:.:||.|:.|::.
Yeast   256 VV---NLWQLLDIKAGLSLRQFMRHFSKRLNGLVLIPFVIYLFWFWVHFTVLNTSGPGDAFMSAE 317

  Fly   434 FQASLDGGLASITKGQPLA-----VVHGSQITLRHTHGRTCWLHSHAAVYPVRYPDKRGSSHQQQ 493
            ||.:|        |..||:     |.:...||::| .....:||||.|.||.||.|.|.||..||
Yeast   318 FQETL--------KDSPLSVDSKTVNYFDIITIKH-QDTDAFLHSHLARYPQRYEDGRISSAGQQ 373

  Fly   494 VTCYSFKDVNNWWLVKRPTKENLVVGDEPDIIRHGEIIQLVHGITSRALNSHDVAAAMTPQCQEV 558
            ||.|:..|.||.|.|..|...::..|....:.:|   |:|.|..|...|.:||||:...|..:|:
Yeast   374 VTGYTHPDFNNQWEVLPPHGSDVGKGQAVLLNQH---IRLRHVATDTYLLAHDVASPFYPTNEEI 435

  Fly   559 SCYI--DYEIKMAGELLWRVEILNRDSEGDIWHAIKSEV---RLVHVSTEASL-KFSGRQLPEWG 617
            :...  :.:.::..|.|:..:.|.:..||   |.:||:.   ||.||.|..:| ..:...||:||
Yeast   436 TTVTLEEGDGELYPETLFAFQPLKKSDEG---HVLKSKTVSFRLFHVDTSVALWTHNDELLPDWG 497

  Fly   618 FNQHEVVADREKAIHEDAIWNVEEHRYTQTEDHRERERQMLTAEMIPTKRTRISFWAKLLELQSK 682
            |.|.|:..:: |.|.....|.|:|  ....::.|:        ..||.....:.|..|.:|.|..
Yeast   498 FQQQEINGNK-KVIDPSNNWVVDE--IVNLDEVRK--------VYIPKVVKPLPFLKKWIETQKS 551

  Fly   683 ML-FQTKSVPNHMYSSMPHEWPLMDKGIAYWLDSQSSAQIYLLGNILLWYTATMGILVYAGLLAF 746
            |. ...|....|.::|.|:.||....|:::|.:.....|||.:|||:.|:...:.:.|:.|::..
Yeast   552 MFEHNNKLSSEHPFASEPYSWPGSLSGVSFWTNGDEKKQIYFIGNIIGWWFQVISLAVFVGIIVA 616

  Fly   747 YAMRRQRLCFDISEQEWQRFVLAGDTFFMGYVMHYIPYFCVDRTLFLHNYLPAFVFKLLLLCFVV 811
            ..:.|.|..:.:::...::.......||:.:..||.|:|.:.|..|||:||||.    |:.|...
Yeast   617 DLITRHRGYYALNKMTREKLYGPLMFFFVSWCCHYFPFFLMARQKFLHHYLPAH----LIACLFS 677

  Fly   812 EHLDYLLRRFCTGRGVH----------------LVRLYRLMLILWLVGVLSIFSKFIPFSYGARK 860
            ..|..::...|....:.                .|:.|.:.|:.....|...|..|.|..||...
Yeast   678 GALWEVIFSDCKSLDLEKDEDISGASYERNPKVYVKPYTVFLVCVSCAVAWFFVYFSPLVYGDVS 742

  Fly   861 MTLNEVRSLRWKD 873
            ::.:||.|..|.|
Yeast   743 LSPSEVVSREWFD 755

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rt	NP_524025.2	PMT	178..421	CDD:396786	89/246 (36%)
		beta-trefoil_MIR_POMT1	453..644	CDD:467752	67/196 (34%)
		PMT_4TMC	674..873	CDD:465056	54/215 (25%)
PMT4	NP_012677.1	PMT	58..305	CDD:396786	89/246 (36%)
		beta-trefoil_MIR_PMT4-like	334..521	CDD:467756	67/196 (34%)
		PMT_4TMC	543..755	CDD:465056	54/215 (25%)