Protein Alignment rt and Pomt2

DIOPT Version :10

• Sequence 1: NP_524025.2
• Gene: rt / 39297
• FlyBaseID: FBgn0003292
• Length: 886
• Species: Drosophila melanogaster
• Sequence 2: NP_001040579.1
• Gene: Pomt2 / 688673
• RGDID: 1586427
• Length: 820
• Species: Rattus norvegicus
• Alignment Length: 840
• Identity: 247/840 - (29%)
• Similarity: 389/840 - (46%)
• Gaps: 103/840 - (12%)

  Fly    82 HLNAPLRGSVNRHTTPTPTPTATPTPVATPKQASPSPTSDRSRSLSRSPSPSRSRSL-SCQKQID 145
            ||..|...|:....|....|.|... :....:..|:.....:.|..|   |.|.||: ...:.:.
  Rat    40 HLETPSYDSLTGQRTRPGVPPARRV-ILRKGRMPPAIGGGLAGSELR---PRRGRSVQQAARAVS 100

  Fly   146 KNSAGAASAEERKTANASSQPFTVNLRIDLFSW-----TLFLLAFGTRFYKLATPPHIVFDELHY 205
            ::....|:..:.|....||:      |.....|     .:.||:|.|||::|..|.||.:||.|:
  Rat   101 RDVVPEAATRKLKRPAWSSR------RFQAAGWWATLAVVTLLSFATRFHRLDQPAHICWDETHF 159

  Fly   206 GKYISMYMRNIFFFDQHPPLGKQLIAGLVSLAGYDGNYTFTRIGEPYSPEMPIFWFRFLPAMCGS 270
            ||..|.|:...||||.||||||.||.....|:||||.:.|.:.|:.|. .......|...|..||
  Rat   160 GKMGSYYINRTFFFDVHPPLGKMLIGLAGYLSGYDGTFLFQKPGDRYE-HHSYMGMRGFCAFLGS 223

  Fly   271 LLAPAVYNLLLEAKLSRWSSALGGLLVVLDNSLLTQSRFVLMESMLLLATTVGIACLLRFQ--RS 333
            .|.|..|..:|:...|..::.|...|:..|...||.|:::|::.:|:......:..::::.  .:
  Rat   224 WLIPFAYLTVLDLSKSFPAALLTAALLTCDTGCLTLSQYILLDPILMFFIMAAMLSMVKYNSFAN 288

  Fly   334 RLGSLEWFFTGTAAAVCLGAAGTVKYVGFLALGLAFYLLCRHLWQLLYDAGLTDRQLWMHAISRL 398
            |..|..|:|..:...:.|..|..||:||...:..........||.|..|..|:...:..|..:|:
  Rat   289 RPFSAPWWFWLSLTGISLAGALGVKFVGLFIIVQVGLNTISDLWHLFGDLSLSLVTVGKHLTARI 353

  Fly   399 LIFVGIPLAVYLGVFYIHFKTLHRAGPHDSIMTSAFQASLDGGL---ASITKGQPLAVVHGSQIT 460
            |..:.:||.:|:.:|.:|...|:::||.|...:|||||.|.|..   |||    |..:.:||.||
  Rat   354 LCLIVLPLVLYVTIFAVHVMVLNKSGPGDGFFSSAFQARLSGNSLHNASI----PEHLAYGSVIT 414

  Fly   461 LRHTHGRTCWLHSHAAVYPVRYPDKRG-SSHQQQVTCYSFKDVNNWWLVKR------PTKENLVV 518
            :::......:||||..:||      .| .:.|||||.|..||.||.|::|:      |...:..|
  Rat   415 VKNLRMAIGYLHSHRHLYP------EGIGARQQQVTTYLHKDYNNLWIIKKYNTNTDPLDPSFPV 473

  Fly   519 GDEPDIIRHGEIIQLVHGITSRALNSHDVAAAMTPQCQEVSCYIDYEIKMAGEL--LWRVEILNR 581
                :.:|||:||:|.|..|:|.|:||...|.:|.:..:|:   .|.|...|:.  .||:|::||
  Rat   474 ----EFVRHGDIIRLEHKETTRNLHSHYHEAPLTRKHYQVT---GYGINGTGDSNDFWRIEVVNR 531

  Fly   582 DSEGDIWHAIKSEVRLVHVSTEASLKFSGRQLPEWGFNQHEVVADREKAIHEDAIWNVEEHRYTQ 646
             ..|:....::|.:|.:|:.|...|..||:.||:||:.|.||..:.......::|||:|||
  Rat   532 -KFGNRIKVLRSRIRFIHLVTGCVLGSSGKILPKWGWEQLEVTCNPYLKETSNSIWNIEEH---- 591

  Fly   647 TEDHRERERQMLTAEMIPTKRTRI-------SFWAKLLELQSKMLFQTKSV--PNHMYSSMPHEW 702
                            |..|...|       ||...|||....|:.....:  .::.::|.|..|
  Rat   592 ----------------INPKLPNISLDVLQPSFPEILLESHMVMIRGNNGLKPKDNEFTSKPWHW 640

  Fly   703 PLMDKGIAYWLDSQSSAQIYLLGNILLWYTATMGILVY--AGLLAFYAMRRQRLCFDISEQEWQR 765
            |:..:|:.:...:.:..::|||||.::|:...:.:::|  .|.....||:| .:......|...:
  Rat   641 PINYQGLRFSGANDTDFRVYLLGNPVVWWLNLVSLVLYLLTGSTIAIAMQR-GIQLPAELQGLTK 704

  Fly   766 FVL-AGDTFFMGYVMHYIPYFCVDRTLFLHNYLPAFVFKLLLLCFVVEHLDYLLRRFCT------ 823
            .:| .|....:|:.:||.|:|.:.|.|:.|:|.||.:|..:|...:   .|.|| |||.
  Rat   705 LLLRGGGQLLLGWTLHYFPFFLMGRVLYFHHYFPAMLFSSMLTGLL---WDTLL-RFCAWALAPS 765

  Fly   824 --GRGVHLVRLYRLMLILWLVGVLSIFSKFIPFSYGARKMTLNEVRS----LRWKDTWDF 877
              ||.:|:|.:..|:|     .....|..|.|.:||.......|..|    |||.::|||
  Rat   766 PLGRRIHMVGILSLLL-----ATAYSFYLFHPLAYGMVGPLAQEPESPMAGLRWLESWDF 820

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rt	NP_524025.2	PMT	178..421	CDD:396786	78/249 (31%)
		beta-trefoil_MIR_POMT1	453..644	CDD:467752	69/199 (35%)
		PMT_4TMC	674..873	CDD:465056	58/215 (27%)
Pomt2	NP_001040579.1	PMT	132..376	CDD:396786	77/244 (32%)
		beta-trefoil_MIR_POMT2	407..593	CDD:467753	69/219 (32%)
		PMT_4TMC	612..816	CDD:465056	58/213 (27%)