DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rt and Sdf2l1

DIOPT Version :9

Sequence 1:	NP_524025.2	Gene:	rt / 39297	FlyBaseID:	FBgn0003292	Length:	886	Species:	Drosophila melanogaster
Sequence 2:	NP_001102903.1	Gene:	Sdf2l1 / 680945	RGDID:	1585844	Length:	220	Species:	Rattus norvegicus

Alignment Length:	197	Identity:	56/197 - (28%)
Similarity:	83/197 - (42%)	Gaps:	47/197 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   440 GGLASITKGQPLAVVHGSQITLRHTHGRTCWLHSHAAVYPVRYPDKRGS-SHQQQVT-CYSFKDV 502
            ||.:..:.|   .|..||.:.|.:||.|. .||||...|        || |.||.|| ..:..|.
  Rat    25 GGASKASAG---LVTCGSVLKLLNTHHRV-RLHSHDIKY--------GSGSGQQSVTGVEASDDA 77

  Fly   503 NNWWLVKRPTKENLVVGDEPDIIRHGEIIQLVHGITSRALNSHDVAAAMTPQCQEVSCYIDYEIK 567
            |::|.::..::.....|..   :|.|:.::|.|.:|.:.|::|...:.::.. ||||.:
  Rat    78 NSYWRIRGGSEGGCPRGLP---VRCGQAVRLTHVLTGKNLHTHHFPSPLSNN-QEVSAF------ 132

  Fly   568 MAGELLWRVEILNRDSEG---DIWHA--------IKSEVRLVHVSTEASLKFSGRQLPEWGFNQH 621
              ||          |.||   |:|..        .::.||..||.|...|..:|.|.......||
  Rat   133 --GE----------DGEGDDLDLWTVRCSGQHWEREASVRFQHVGTSVFLSVTGEQYGNPIRGQH 185

  Fly   622 EV 623
            ||
  Rat   186 EV 187

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rt	NP_524025.2	PMT	178..421	CDD:280519
		PMT1	180..877	CDD:224839	56/197 (28%)
		MIR	452..508	CDD:197746	22/57 (39%)
		MIR	522..578	CDD:197746	13/55 (24%)
		MIR	586..642	CDD:197746	14/46 (30%)
		PMT_4TMC	672..875	CDD:292810
Sdf2l1	NP_001102903.1	PMT1	<52..>199	CDD:224839	46/166 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1928
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810