DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rt and sdf2

DIOPT Version :9

Sequence 1:	NP_524025.2	Gene:	rt / 39297	FlyBaseID:	FBgn0003292	Length:	886	Species:	Drosophila melanogaster
Sequence 2:	NP_956333.1	Gene:	sdf2 / 336879	ZFINID:	ZDB-GENE-030131-8823	Length:	222	Species:	Danio rerio

Alignment Length:	234	Identity:	66/234 - (28%)
Similarity:	102/234 - (43%)	Gaps:	36/234 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   425 PHDSIMTSAFQASLDGGLASITKGQPLAVVHGSQITLRHTHGRTCWLHSHAAVYPVRYPDKRGS- 488
            |...:::..|..:|...:..:|.|..:.:     |.::|    ...||||    .|||    ||
Zfish    12 PLTVLLSCVFTLTLCSEMNCVTCGSVVKL-----INVKH----NVRLHSH----DVRY----GSG 59

  Fly   489 SHQQQVT-CYSFKDVNNWWLVKRPTKENLVVGDEPDIIRHGEIIQLVHGITSRALNSHDVAAAMT 552
            |.||.|| ..:.:|.|::|.| |.|.::......|  :|.|:.|:|.|..|.|.|:||...:.::
Zfish    60 SGQQSVTGVTTVEDSNSYWSV-RGTSDHSCHRGTP--VRCGQNIRLTHVNTGRNLHSHYFTSPLS 121

  Fly   553 PQCQEVSCYIDYEIKMAGELL--WRVEILNRDSEGDIWHAIKSEVRLVHVSTEASLKFSGRQLPE 615
            .. ||||.:.:   ...|:.|  |.|..:     |.||...:| ||..|.:|||.|..:|.|...
Zfish   122 SN-QEVSAFGE---NGEGDHLDEWTVLCV-----GSIWQRDES-VRFQHTATEALLSVTGEQFGR 176

  Fly   616 WGFNQHEVVADREKAIHEDAIWNVEEHRYTQTEDHRERE 654
            ....|.||......:.|  :.|...|..:.:..:...|:
Zfish   177 PIHGQREVHGMMVSSSH--SYWRTMEGIFIKPSEAGSRD 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rt	NP_524025.2	PMT	178..421	CDD:280519
		PMT1	180..877	CDD:224839	66/234 (28%)
		MIR	452..508	CDD:197746	19/57 (33%)
		MIR	522..578	CDD:197746	19/57 (33%)
		MIR	586..642	CDD:197746	17/55 (31%)
		PMT_4TMC	672..875	CDD:292810
sdf2	NP_956333.1	MIR	32..80	CDD:197746	21/64 (33%)
		MIR	91..146	CDD:197746	19/60 (32%)
		MIR	155..200	CDD:197746	15/47 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1928
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810