Protein Alignment rt and ogm1

DIOPT Version :10

• Sequence 1: NP_524025.2
• Gene: rt / 39297
• FlyBaseID: FBgn0003292
• Length: 886
• Species: Drosophila melanogaster
• Sequence 2: NP_593237.1
• Gene: ogm1 / 2541418
• PomBaseID: SPAC22A12.07C
• Length: 893
• Species: Schizosaccharomyces pombe
• Alignment Length: 742
• Identity: 184/742 - (24%)
• Similarity: 330/742 - (44%)
• Gaps: 99/742 - (13%)

  Fly   180 LFLLAFGTRFYKLATPPHIVFDELHYGKYISMYMRNIFFFDQHPPLGKQLIAGLVSLAG--YDGN 242
            |.::||..|..:|..|..:||:||.|..|...|:.|....|.:|||||.|.:.:.:|.|  |:.|
pombe    40 LTVVAFCVRAQRLMNPAKVVFEELRYYNYAVDYVNNKLLMDVYPPLGKLLFSLVAALTGNKYELN 104

  Fly   243 YTFTRIGEPYSPEMPIFWFRFLPAMCGSLLAPAVYNLLLEAKLSRWSSALGGLLVVLDNSLLTQS 307
             |....|:.|......:..|....:.||||.|.:|..:.....|:.:::|..|.|:.||.|:|.|
pombe   105 -TLDEPGQQYPFTDVAYSMRLFTCLLGSLLVPLMYGTVYFPTKSKTAASLAALFVIFDNGLITMS 168

  Fly   308 RFVLME--SMLLLATTVGIACLLRFQRSRLGSLEWFFTGTAAAVCLGAAGTVKYVGFLALGLAFY 370
            |::::|  ::..::.|.....:...|:.|..||.|..:..:..|.||.|.:.|.......|....
pombe   169 RYIMIEIPALYFMSLTAFYWSVYEAQQKRPFSLRWHTSLLSTGVALGLALSTKLSAMFTFGWLLI 233

  Fly   371 LLCRHLWQLLYDAGLTDRQLWMHAISRLLIFVGIPLAVYLGVFYIHFKTLHRAGPHDSIMTSAFQ 435
            |...|||.||.|..:...::..|..|.:...:|:|:.|||.||.:|....::|...|:.:....:
pombe   234 LAAFHLWNLLGDLSVPMYRIVKHLFSYIFYLIGVPITVYLAVFAVHSHIAYKASVADAFLPPEHR 298

  Fly   436 ASLDGGLASITKGQPLAVVHGSQITLRHT---HGRTCWLHSHAAVYPVRYPDKRGSSHQQQVTCY 497
            .:|.|....   .|...|.:||.:|:|:.   ||   :|||...:||       ..:.||.::..
pombe   299 HALAGNRFD---DQFADVAYGSLVTIRNAIPEHG---YLHSSELLYP-------EGTEQQIISLV 350

  Fly   498 SFKDVNNWWLVKRP-----TKENLVVGDEPDIIRHGEIIQLVHGITSRALNSHDVAAAMTPQ--C 555
            ...:.|..|:::..     .:.|:      ::::.|.:::|.|.:|.|||:||:....::..  .
pombe   351 DEPNQNALWIIEHEHSQDNNRSNI------ELLKDGSVVRLRHVMTGRALHSHEHKPIVSNNDWQ 409

  Fly   556 QEVSCYIDYEIKMAGELLWRVEILNRDSEGDIWHA--------IKSEVRLVHVSTEASLKFSGRQ 612
            .|.|.|..:..:.....|:|::||.:.|:    ||        :.::.||:||.....|..|.|:
pombe   410 LEASAYGGFGFEGDANDLFRIQILEKKSK----HATSNGTVETLNTKFRLIHVFANCELMSSHRR 470

  Fly   613 LPEWGFNQHEVVADREKAIHEDAIWNVEEHRYTQTEDHRERERQMLTAEMIPTKRTRIS-----F 672
            .|:||..|.||...| ..:.....|.:|.:.:                :.:|:...:|:     |
pombe   471 FPDWGDYQREVTCCR-NCVERSTTWFIESNYH----------------DGLPSDSRKITYRKPGF 518

  Fly   673 WAKLLELQSKM-LFQTKSVPNHMYSSMPHEWPLMDKGIAYWLDSQSSAQIYLLGNILLWYTATMG 736
            ....:|....| |...|....|:|.|....|||:...:.::.:..  .|::.:||..:|| :.:.
pombe   519 LESFVEHNKLMWLKDRKMGDGHVYESSALTWPLLLGPLRFFYEQH--LQVFFMGNPFVWY-SVIS 580

  Fly   737 ILVYAGLLAFYAMRRQRLCF-DISEQEWQ------RFVLAGDTFFMGYVMHYIPYFCVDRTLFLH 794
            ::.:..::..:.:.|..|.: |.....:.      :||:|       :::|:.||......:||:
pombe   581 LVAFFVIVQIFCLARWNLGYNDFGPSAFHYNYNIGKFVVA-------WLLHWAPYILETDRVFLY 638

  Fly   795 NYLPAFVFKLLLLCFVVEHLDYLLRRFCTGRGVHLVR-LYRLMLILWLVGVLSIFSKFIPFSYGA 858
            :||||..|.:..|......|         |..|...| .|:.:.::.:..:..::..:.||:| .
pombe   639 HYLPALYFGIAALGVSWSFL---------GNAVFGNRTAYKALSVIIMALMFLVYRLYSPFTY-M 693

  Fly   859 RKMTLNEVRSLRWKDTWDFVLHKNHHL 885
            ..:|.:..|:|..|.:|:|  |.|.:|
pombe   694 TTLTKSSCRALELKGSWNF--HCNTYL 718

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rt	NP_524025.2	PMT	178..421	CDD:396786	75/244 (31%)
		beta-trefoil_MIR_POMT1	453..644	CDD:467752	52/208 (25%)
		PMT_4TMC	674..873	CDD:465056	43/207 (21%)
ogm1	NP_593237.1	PMT	38..284	CDD:396786	75/244 (31%)
		beta-trefoil_MIR_PMT1-like	313..501	CDD:467754	52/208 (25%)
		PMT_4TMC	522..707	CDD:465056	43/204 (21%)