Protein Alignment rt and SDF2L1

DIOPT Version :9

• Sequence 1: NP_524025.2
• Gene: rt / 39297
• FlyBaseID: FBgn0003292
• Length: 886
• Species: Drosophila melanogaster
• Sequence 2: NP_071327.2
• Gene: SDF2L1 / 23753
• HGNCID: 10676
• Length: 221
• Species: Homo sapiens
• Alignment Length: 197
• Identity: 57/197 - (28%)
• Similarity: 84/197 - (42%)
• Gaps: 46/197 - (23%)

  Fly   440 GGLASITKGQPLAVVHGSQITLRHTHGRTCWLHSHAAVYPVRYPDKRGS-SHQQQVT-CYSFKDV 502
            ||.|:.|..:  .|..||.:.|.:||.|. .||||...|        || |.||.|| ..:..|.
Human    25 GGGAAKTGAE--LVTCGSVLKLLNTHHRV-RLHSHDIKY--------GSGSGQQSVTGVEASDDA 78

  Fly   503 NNWWLVKRPTKENLVVGDEPDIIRHGEIIQLVHGITSRALNSHDVAAAMTPQCQEVSCYIDYEIK 567
            |::|.::..::.....|..   :|.|:.::|.|.:|.:.|::|...:.::.. ||||.:
Human    79 NSYWRIRGGSEGGCPRGSP---VRCGQAVRLTHVLTGKNLHTHHFPSPLSNN-QEVSAF------ 133

  Fly   568 MAGELLWRVEILNRDSEG---DIWHA--------IKSEVRLVHVSTEASLKFSGRQLPEWGFNQH 621
              ||          |.||   |:|..        .::.||..||.|...|..:|.|.......||
Human   134 --GE----------DGEGDDLDLWTVRCSGQHWEREAAVRFQHVGTSVFLSVTGEQYGSPIRGQH 186

  Fly   622 EV 623
            ||
Human   187 EV 188

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rt	NP_524025.2	PMT	178..421	CDD:280519
		PMT1	180..877	CDD:224839	57/197 (29%)
		MIR	452..508	CDD:197746	22/57 (39%)
		MIR	522..578	CDD:197746	13/55 (24%)
		MIR	586..642	CDD:197746	14/46 (30%)
		PMT_4TMC	672..875	CDD:292810
SDF2L1	NP_071327.2	PMT_4TMC	<53..>200	CDD:330524	46/166 (28%)
		Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138	218..221

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1928
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810