Protein Alignment rt and Pomt2

DIOPT Version :10

• Sequence 1: NP_524025.2
• Gene: rt / 39297
• FlyBaseID: FBgn0003292
• Length: 886
• Species: Drosophila melanogaster
• Sequence 2: XP_011242390.2
• Gene: Pomt2 / 217734
• MGIID: 2444430
• Length: 837
• Species: Mus musculus
• Alignment Length: 900
• Identity: 259/900 - (28%)
• Similarity: 399/900 - (44%)
• Gaps: 162/900 - (18%)

  Fly    67 ARALTMLNCCVDVNCHLNAP-------LRGSVNRHTTPTPTPTATPTPVATPKQASPSPTSDRSR 124
            |||.|.          |:||       |||.......|....|.:..|: |.::..|.....|..
Mouse    11 ARAATT----------LSAPPRARGPALRGKRRELQIPWHLETPSYDPL-TGQRTRPGVPPARRV 64

  Fly   125 SLSRSPSPS-----------RSRSLSCQKQ----IDKNSAGAASAEERKTANASSQPFTVNLRID 174
            .|.:...|.           |.|...|..|    :.::....|:|.:.|....||:      |..
Mouse    65 ILRKGRMPPAIGGGLAGSELRPRRGRCVPQAARAVSRDVVPQAAARKLKRPAWSSR------RFQ 123

  Fly   175 LFSW-----TLFLLAFGTRFYKLATPPHIVFDELHYGKYISMYMRNIFFFDQHPPLGKQLIAGLV 234
            ...|     .:.||:|.|||::|..|.||.:||.|:||..|.|:...||||.||||||.||....
Mouse   124 AAGWWATLAVVTLLSFATRFHRLDQPAHICWDETHFGKMGSYYINRTFFFDVHPPLGKMLIGLAG 188

  Fly   235 SLAGYDGNYTFTRIGEPYSPEMPIFWFRFLPAMCGSLLAPAVYNLLLEAKLSRWSSALGGLLVVL 299
            .|:||||.:.|.:.|:.|. .......|...|..||.|.|..|..:|:...|..::.|...|:..
Mouse   189 YLSGYDGTFLFQKPGDRYE-HHSYMGMRGFCAFLGSWLIPFAYLTVLDLSKSFPAALLTAALLTF 252

  Fly   300 DNSLLTQSRFVLMESMLLLATTVGIACLLRFQ--RSRLGSLEWFFTGTAAAVCLGAAGTVKYVGF 362
            |...||.|:::|::.:|:......:..::::.  .:|..|..|:|..:...:.|..|..||:||.
Mouse   253 DTGCLTLSQYILLDPILMFFIMAAMLSMVKYNSCANRPFSAPWWFWLSLTGISLAGALGVKFVGL 317

  Fly   363 LALGLAFYLLCRHLWQLLYDAGLTDRQLWMHAISRLLIFVGIPLAVYLGVFYIHFKTLHRAGPHD 427
            ..:..........||.|..|..|:...:..|..:|:|..:.:||.:|:.:|.:|...|:::||.|
Mouse   318 FIIVQVGLNTISDLWHLFGDLSLSLVTVGKHLTARILCLIVLPLVLYVTIFAVHVMVLNKSGPGD 382

  Fly   428 SIMTSAFQASLDGGL---ASITKGQPLAVVHGSQITLRHTHGRTCWLHSHAAVYPVRYPDKRG-S 488
            ...:|||||.|.|..   |||    |..:.:||.||:::......:||||..:||      .| .
Mouse   383 GFFSSAFQARLSGNSLHNASI----PEHLAYGSVITVKNLRMAIGYLHSHRHLYP------EGIG 437

  Fly   489 SHQQQVTCYSFKDVNNWWLVKR------PTKENLVVGDEPDIIRHGEIIQLVHGITSRALNSHDV 547
            :.|||||.|..||.||.|::|:      |...:..|    :.:|||:||:|.|..|:|.|:||..
Mouse   438 ARQQQVTTYLHKDYNNLWIIKKYNANTDPLDPSFPV----EFVRHGDIIRLEHKETTRNLHSHYH 498

  Fly   548 AAAMTPQCQEVSCYIDYEIKMAGEL--LWRVEILNRDSEGDIWHAIKSEVRLVHVSTEASLKFSG 610
            .|.:|.:..:|:   .|.|...|:.  .||:|::|| ..|:....::|.:||:|:.|...|..||
Mouse   499 EAPLTRKHYQVT---GYGINGTGDSNDFWRIEVVNR-KFGNRIKVLRSRIRLIHLVTGCVLGSSG 559

  Fly   611 RQLPEWGFNQHEVVADREKAIHEDAIWNVEEHRYTQTEDHRERERQMLTAEMIPTKRTRI----- 670
            :.||:||:.|.||..........::|||:|||                    |..|...|
Mouse   560 KILPKWGWEQLEVTCTPYLKETTNSIWNIEEH--------------------INPKLPNISLDVL 604

  Fly   671 --SFWAKLLELQSKMLFQTKSV--PNHMYSSMPHEWPLMDKGIAYWLDSQSSAQIYLLGNILLWY 731
              ||...|||....|:.....:  .::.::|.|..||:..:|:.:...:.:..::|||||.::|:
Mouse   605 QPSFPEILLESHMVMIRGNNGLKPKDNEFTSKPWHWPINYQGLRFSGANDTDFRVYLLGNPVVWW 669

  Fly   732 TATMGILVY--AGLLAFYAMRRQRLCFDISEQEWQRFVL-AGDTFFMGYVMHYIPYFCVDRTLFL 793
            ...:.|::|  :|.....||:| .:......|...:.:| .|....:|:::||.|:|.:.|.|:.
Mouse   670 LNLVSIVLYLLSGSTIAVAMQR-GIQLPAELQGLTKVLLRGGGQLLLGWMLHYFPFFLMGRILYF 733

  Fly   794 HNYLPAFVFKLLLLCFVVEHLDYLLRRFCTGR-GVHLVRLYRLML---ILW-------------- 840
            |:|.||.:|..:|                ||. |..|:..|..:|   |||
Mouse   734 HHYFPAMLFSSML----------------TGSPGAVLIGWYMSLLSIGILWDTLLRLCAWGLAPS 782

  Fly   841 -------LVGVLSI-------FSKFIPFSYGARKMTLNEVRS----LRWKDTWDF 877
                   .||:||:       |..|.|.:||.......|..|    |||.::|||
Mouse   783 PLGRRIHAVGILSLLLTTAYSFYLFHPLAYGMVGPLAQEPESPMAGLRWLESWDF 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rt	NP_524025.2	PMT	178..421	CDD:396786	78/249 (31%)
		beta-trefoil_MIR_POMT1	453..644	CDD:467752	70/199 (35%)
		PMT_4TMC	674..873	CDD:465056	60/239 (25%)
Pomt2	XP_011242390.2	PMT	132..376	CDD:396786	77/244 (32%)
		beta-trefoil_MIR_POMT2	407..593	CDD:467753	70/219 (32%)
		PMT_4TMC	612..833	CDD:465056	60/237 (25%)