DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rt and R12E2.13

DIOPT Version :9

Sequence 1:	NP_524025.2	Gene:	rt / 39297	FlyBaseID:	FBgn0003292	Length:	886	Species:	Drosophila melanogaster
Sequence 2:	NP_491320.1	Gene:	R12E2.13 / 172010	WormBaseID:	WBGene00020038	Length:	206	Species:	Caenorhabditis elegans

Alignment Length:	187	Identity:	59/187 - (31%)
Similarity:	83/187 - (44%)	Gaps:	27/187 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   471 LHSHAAVYPVRYPDKRGS-SHQQQVTCY-SFKDVNNWWLVKRPTKENLVVGDEPDIIRHGEIIQL 533
            ||||...|        || |.||.||.. :..|:|:.|.:..........|   |.|:.|:.|:|
Worm    43 LHSHDVKY--------GSGSGQQSVTAVKNSDDINSHWQIFPALNAKCNRG---DAIKCGDKIRL 96

  Fly   534 VHGITSRALNSHDVAAAMTPQCQEVSCYIDYEIKMAGELLWRVEILNRDSEGDIWHAIKSE-VRL 597
            .|..|...|:||...|.::.|.||||.:........|: .|.| |.|    ||.|  ::|| .:|
Worm    97 KHLTTGTFLHSHHFTAPLSKQHQEVSAFGSEAESDTGD-DWTV-ICN----GDEW--LESEQFKL 153

  Fly   598 VHVSTEASLKFSGRQLPEWGFNQHEVVADREKAIHEDAIWNVEEHRYTQTEDHRERE 654
            .|..|.:.|..||:|.......|.|||.  ..:|...:.|.|.|..|.:   |::::
Worm   154 RHAVTGSYLSLSGQQFGRPIHGQREVVG--TDSITGGSAWKVAEGIYIK---HQQKD 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rt	NP_524025.2	PMT	178..421	CDD:280519
		PMT1	180..877	CDD:224839	59/187 (32%)
		MIR	452..508	CDD:197746	15/38 (39%)
		MIR	522..578	CDD:197746	19/55 (35%)
		MIR	586..642	CDD:197746	18/56 (32%)
		PMT_4TMC	672..875	CDD:292810
R12E2.13	NP_491320.1	MIR	23..77	CDD:197746	15/41 (37%)
		MIR	34..180	CDD:280906	51/155 (33%)
		MIR	85..141	CDD:197746	21/60 (35%)
		MIR	143..195	CDD:197746	18/55 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1928
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810